Results 41 to 50 of about 7,666 (128)

Janus Kinase Inhibitors During Pregnancy and Adverse Drug Reactions: A Pharmacovigilance Disproportionality Analysis in VigiBase

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Janus kinase inhibitors (JAKIs) are immunomodulatory drugs used for autoimmune and inflammatory conditions. Their potential impact on pregnancy and fetal development remains a concern due to placental transfer and potential disruption of cytokine and growth factor signaling, with limited human data.
Nazanin Abolhassani, Roberta Noseda, Kim Dao, François R. Girardin, Francesca Bedussi, Alessandro Ceschi, Alice Panchaud, Ursula Winterfeld   +7 more
wiley   +1 more source

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges

Journal of Extracellular Vesicles, Volume 14, Issue 9, September 2025.
ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Asja Garling, Frédéric Auvray, Mathieu Epardaud, Éric Oswald, Priscilla Branchu   +4 more
wiley   +1 more source

Waning vaccine immunity in teenagers primed with whole cell and acellular pertussis vaccine: recent epidemiology

, 2014
The recent epidemics of pertussis (whooping cough) in parts of the USA and Australia have led to the largest numbers of annual cases reported in over half a century.
Snelling, Thomas, Frith, K., Snelling, Thomas L, McIntyre, Peter, Stephen B Lambert, Peter B McIntyre, Snelling, Thomas L., Lambert, Stephen B, Lambert, S., Thomas L Snelling, McIntyre, Peter B, McIntyre, Peter B., Lambert, Stephen B., Grimwood, K., Sheridan, Sarah L., Keith Grimwood, Sheridan, Sarah L, Grimwood, Keith, Frith, Katie, Katie Frith, McIntyre, P., Sarah L Sheridan, Sheridan, S.   +22 more
core   +1 more source

Advance system testing: Vaccine benefit studies using multi-country electronic health data - The example of pertussis vaccination

, 2020
The Accelerated Development of VAccine benefit-risk Collaboration in Europe (ADVANCE), a public-private consortium, implemented and tested a distributed network system for the generation of evidence on the benefits-risks of marketed vaccines in Europe ...
de, Lusignan S, Martín-Merino, E, Correa, A, Tramontan, L, de, Ridder M, McGee, C, Duarte-Salles, T, Huerta-Alvarez, C, Braeye, T, Tin, Tin Htar M   +9 more
core   +1 more source

Management of COPD With Cardiovascular Risk in Asia: A Review by the Asian Pacific Society of Respirology COPD Assembly

Respirology, Volume 30, Issue 9, Page 817-830, September 2025.
ABSTRACT Chronic obstructive pulmonary disease (COPD) has a high burden in Asia. These patients are also susceptible to various cardiovascular diseases (CVD). A panel of expert Asian pulmonologists explored the published literature to understand the impact of COPD and CVD on each other and to identify the cardiopulmonary risk factors in the region. The
Chin Kook Rhee, Fanny Wai San Ko, Vu Van Giap, Theerasuk Kawamatawong, Jung‐Kyu Lee, Kazuto Matsunaga, Helmy Haja Mydin, Yong‐Kek Pang, Diahn‐Warng Perng, Myla Salazar‐Supe, Yoko Shibata, David Sim, Naoya Tanabe, Augustine Tee, Hao‐Chien Wang, Yen‐Wen Wu, Faisal Yunus   +16 more
wiley   +1 more source

Clinical progress note: Pertussis

Journal of Hospital Medicine, Volume 20, Issue 8, Page 862-865, August 2025.
Visual Abstract Abstract Pertussis, commonly known as whooping cough, is a vaccine‐preventable respiratory disease with rising incidence due to declining vaccination rates and waning immunity. The most severe disease course is seen in unvaccinated or incompletely vaccinated infants less than 2 months of age, accounting for the largest burden of ...
Samantha Hanna, Nicole Samies
wiley   +1 more source

Replacing ADT With dTpa in Queensland Emergency Departments: Another Opportunity for Pertussis Control?

Emergency Medicine Australasia, Volume 38, Issue 1, February 2026.
Michael D. Nissen, Faye Jordan, Polash Adhikari, Sebastian Vernal, Luis Furuya‐Kanamori   +4 more
wiley   +1 more source

Booster vaccination after neonatal priming with acellular pertussis vaccine

, 2010
After a birth dose of acellular pertussis (aP) and diphtheria (DT)aP-hepatitis B virus (HBV)-inactivated polio vaccine (IPV)/Haemophilus influenza type b (Hib) at 2, 4, and 6 months, a booster dose of DTaP-HBV-IPV/Hib at 12 to 23 months induced strong ...
Knuf, Markus, Meyer, Claudius U., Zepp, Fred, Collard, Alix, Kieninger, Dorothee, Schmitt, Heinz-Josef, Siegrist, Claire-Anne, Jacquet, Jeanne-Marie   +7 more
core   +1 more source

REACTOGENICITY OF ACELLULAR PERTUSSIS VACCINE AND THE POSSIBILITY OF ITS USE IN ELDER CHILDREN

, 2008
As is know, in the past few years, the incidence of pertussis has increased again. The article reveals the reasons of this phenomenon and the possible solutions for this problem.
A.G. Gaivoronskaya, M.G. Galitskaya, M.V. Fedoseenko, L.S. Namazova, S.G. Aleksina   +4 more
core   +1 more source

Meta-analysis of acellular pertussis vaccines.

, 2018
This figure represents the relative risk (OR) of pertussis infection occurring at different time points after vaccination. The I2 values (i.e. Higgin’s I2) quantifies the proportion of heterogeneity and dispersion in the meta-analytic model.
Jason K. H. Lee (3611741), Michael D. Decker (5410280), David R. Johnson (1905763), Antigona Tomovici (5410283), Denis Macina (5400659), Jianhong Wu (88681), Hossein Zivaripiran (5410277), Ayman Chit (776713), Thomas Shin (5228501)   +8 more
core   +1 more source