Catalytic Enantioselective Intramolecular Aza‐Michael Addition to α,β‐Unsaturated Esters
Angewandte Chemie, EarlyView.A general method for accessing enantioenriched saturated N‐heterocycles via a catalytic enantioselective intramolecular aza‐Michael reaction to α,β‐unsaturated esters is described. A superbasic bifunctional iminophosphorane (BIMP) catalyst was key to enabling reactivity of the high pKa sulfonamide pronucleophile, whilst delivering good to excellent ...
Evan G. W. Rutter +5 more
wiley +2 more sources
Effects of contrasting herbivore cues on seedlings of a long-lived woody tree: growth, chemistry, and resistance to herbivores. [PDF]
AoB PlantsBhavanam SP, Preisser EL, Orians CM.
europepmc +1 more source
Climate change and perennial crop production: Evidence of yield impact and adaptation in California
American Journal of Agricultural Economics, EarlyView.Abstract Perennial crops are economically important. They contribute to food security, providing essential nutrients that are often lacking in annual crops, and provide additional environmental benefits compared with annual crops. Despite their importance, empirical research on the impacts of climate change and adaptation on perennial crops remains ...
Yuanyuan Wen +2 more
wiley +1 more source
Dietary supplementation with Acer truncatum seed modulates lipid profiles and enriches unsaturated fatty acids in egg yolk of laying hens. [PDF]
Poult SciRen D +5 more
europepmc +1 more source
Animal models of idiopathic membranous nephropathy: Recent advances and future perspectives
Animal Models and Experimental Medicine, EarlyView.This review focuses on the evolution of idiopathic membranous nephropathy (IMN) animal models from traditional approaches (Heymann nephritis, C‐BSA, APA) to antigen‐specific models (PLA2R, THSD7A), critically evaluating their advances and limitations in replicating human IMN pathology.
Qiuying Liu +6 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Gut microbiota from patients with type 2 diabetes induced early diabetes‐like phenotypes in germ‐free mice, including progressive glucose intolerance and mild renal injury. Longitudinal profiling revealed persistent dysbiosis preceding stable metabolic dysfunction, with coordinated fecal and plasma metabolite alterations and a prominent L‐Dopa ...
Jianghao Feng +6 more
wiley +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Emission Dynamics of Constitutive and Herbivore-induced Plant Volatiles from Norway Maple (Acer platanoides) Trunk Infested by the Asian Longhorned Beetle (Anoplophora glabripennis (Motschulsky)). [PDF]
J Chem EcolBraun J +4 more
europepmc +1 more source
Belowground and Aboveground Responses to Mixed Metal Contamination in Native Central European Trees in Relation to the Species-Specific Autecology. [PDF]
Plants (Basel)Günthardt-Goerg MS +3 more
europepmc +1 more source
From Glacial Refugia to Future Shifts: Unraveling the Spatiotemporal Dynamics of Endangered <i>Acer sutchuenense</i> Franch. Under Climate Change. [PDF]
Biology (Basel)Xia X +5 more
europepmc +1 more source