Results 41 to 50 of about 181,324 (347)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

The Scottish Intercollegiate Guidelines Network (SIGN) 157: Guidelines on Risk Reduction and Management of Delirium

Medicina, 2019
The Scottish Intercollegiate Guidelines Network (SIGN) guideline on delirium is a major advance on existing guidelines on this condition. This is particularly important given the evidence it is frequently under-diagnosed and inadequately managed despite ...
Roy L. Soiza, Phyo K. Myint
doaj   +1 more source

Kamusal Alanın Yeni Yüzü Ekşi Sözlük Üzerinden Toplumsal Cinsiyet, İktidar ve Beden Analizi

Erciyes İletişim Dergisi, 2020
İletişim teknolojilerinin gelişmesi toplumsal yaşamın bütün alanlarını köklü bir dönüşüm ile karşı karşıya getirmiştir. Geleneksel sözlük anlayışı da bu değişim ve dönüşüme ayak uydurmuş, e-sözlük anlayışı oldukça popülerlik kazanmıştır.
Tuğba Metin Açer
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

A validation study of the Chinese-Cantonese Addenbrooke’s Cognitive Examination Revised (C-ACER)

Neuropsychiatric Disease and Treatment, 2013
Background There is no valid instrument for multidomain cognitive assessment to aid the detection of mild cognitive impairment (MCI) and mild dementia in Hong Kong. This study aimed to validate the Cantonese Addenbrooke’s Cognitive Examination Revised (C-
LL Wong, Cc Chan, Jl Leung, CY Yung, K. Wu, Syy Cheung, C. Lam   +6 more
semanticscholar   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Institutional foundations of interaction between domestic and foreign nuclear energy markets of the Russian Federation

Управление
Nuclear energy occupies a special place in the energy balance of Russia, being not only a key element of ensuring internal energy security, but also an essential tool for implementing the country’s foreign economic and geopolitical strategy.
A. B. Mottaeva
doaj   +1 more source

The Effect of Soybean Peptides on Improving Quality and the ACE Inhibitory Bioactivity of Extruded Rice [PDF]

, 2022
Shuangdi Hou, Jiafeng Zhao, Yuan Zu, Jiaxuan Zheng, Chunyu Wang, Xia Liu   +5 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Evaluation of growth and ornamental value of 33 maple species on the basis of the research at Rogów Arboretum, Poland

Folia Horticulturae
Maples—Acer L.—belong to one of the most species-rich and valuable genera of trees in landscape architecture. They exhibit a wide range of morphological, ornamental, cultivation and habitat-related characteristics.
Banaszczak Piotr, Borowski Jacek, Sławski Marek   +2 more
doaj   +1 more source