Results 81 to 90 of about 159,161 (308)

el-Keşşâfı Çerçevesinde Zemahşerî'nin Velâyete Bakışı ve Tasavvufun Velâyet Düşüncesiyle Mukāyesesi

open access: yesSufiyye
Kur’ân-ı Kerîm’de velâyet kavramı, her disiplinin kendi konusuna göre farklı bir yönüne işâret edebileceği kadar çeşitli anlamlarda kullanılmıştır.
Abdulrahman Acer
doaj   +1 more source

Mysteriet ACER

open access: yes, 2022
I Norge har strøm alltid vært billig sammenlignet med andre land i Europa, det er noe vi har vært stolt over. Få nordmenn har hatt bekymringer for høye strømregninger, som ville kunne gå på bekostning av andre kostnader. Kraftkrevende industri har unngått usikkerhet for hvilke konsekvenser det kan ha for dem.
openaire   +1 more source

Antagonistic Ubiquitin Switching by USP7 and RNF40 Orchestrates KDM6A Homeostasis to License Coronavirus Susceptibility

open access: yesAdvanced Science, EarlyView.
We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang   +9 more
wiley   +1 more source

New Insight into the Phylogenetics and Morphometrics of the Genus Acer L. (Sapindaceae) Native to Türkiye

open access: yesForestist
Comprehending the phylogeny and evolutionary history of the Acer genus through regional studies is crucial for clarifying its biogeographical patterns. This study investigates the taxonomic status, morphological diversity, and phylogenetic relationships
Pelin Acar   +5 more
doaj   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

open access: yesAdvanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang   +12 more
wiley   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan   +17 more
wiley   +1 more source

Bioinspired Adaptive Leg‐Claw Enables Robust Perching and Grasping for UAVs

open access: yesAdvanced Science, EarlyView.
Inspired by owl limb morphology and bat roosting behavior, this study presents a bioinspired adaptive leg‐claw mechanism that enables UAVs to perform robust and versatile perching and grasping. The design integrates a four‐link tibial structure, tension‐driven deformable feet, and active control, enabling stable perching on various branches and ...
Tianyu Cheng   +6 more
wiley   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

PLACE OF REFORMS IN WESTERN STRUCTURING PROCESS OF OTTOMAN STATE AND THEIR EFFECT ON MODERNIZATION(1718-1789)

open access: yesZeitschrift für die Welt der Türken, 2010
When the crackle sounds started to be heard after the middle of the 17th century, that this wasn’t a temporary sound was understood. In order to understood the reason of these illnesses, old laws and sources were being examined and these were being told ...
Zabit ACER
doaj  

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