Results 211 to 220 of about 21,852 (266)

Anticancer Evaluation of Novel Quinazolinone Acetamides: Synthesis and Characterization.

Anti-Cancer Agents in Medicinal Chemistry, 2021
BACKGROUND According to the global cancer report of 2019, the burden of cancer will exceed more than 18 million becoming one of the major causes of global mortality rate.
Farhana Hakima, R. Salfi, D. Bhikshapathi, Abdullah Khan   +3 more
semanticscholar   +1 more source

Sustainable Approach to Azaheterocyclic Acetamides by Decarboxylative Aminoformylation

, 2020
A green and efficient synthesis of azaheterocyclic acetamides has been developed that significantly reduces the consumption of nitrogen-containing reagents from more than 20 equiv in previously rep...
Zhenxing Zhang, Chunqi Jia, Xiang-tao Kong, Muzammal Hussain, Zhenyu Liu, Wanqing Liang, Ling Jiang, Hao Jiang, Junyan Ma   +8 more
semanticscholar   +1 more source

Synthesis of 2-(1H-Indol-2-yl)acetamides via Bronsted Acid-Assisted Cyclization Cascade.

Journal of Organic Chemistry, 2020
Efficient and straightforward Bronsted-acid mediated cascade process was developed, involving cyclization of readily available beta-ketonitriles into 2-aminofurans and their subsequent recyclization into 2-(1H-indol-2-yl)acetamides is developed.
N. Aksenov, D. Aksenov, A. A. Skomorokhov, Lidiya A Prityko, Alexander V. Aksenov, Georgii D Griaznov, M. Rubin   +6 more
semanticscholar   +1 more source

Synthesis and biological evaluation of a new series of benzofuran‐1,3,4‐oxadiazole containing 1,2,3‐triazole‐acetamides as potential α‐glucosidase inhibitors

Journal of biochemical and molecular toxicology, 2020
A series of new benzofuran‐1,3,4‐oxadiazole containing 1,2,3‐triazole‐acetamides 12a‐n as potential anti‐α‐glucosidase agents were designed and synthesized.
Fahimeh Abedinifar, M. Mohammadi‐Khanaposhtani, Nafise Asemanipoor, Somayeh Mojtabavi, M. Faramarzi, M. Mahdavi, M. Biglar, B. Larijani, H. Hamedifar, Mirhamed Hajimiri   +9 more
semanticscholar   +1 more source

Acetamide hydrochloride

Acta Crystallographica Section C Crystal Structure Communications, 1994
化學系 ; 理學院 ...
Luo, Fen-Tair, Hsieh, Li-Chen, Liu, Ling-Kang   +2 more
openaire   +1 more source

NBE-Controlled Palladium-Catalyzed Interannular Selective C-H Silylation: Access to Divergent Silicon-Containing 1,1'-Biaryl-2-Acetamides.

Organic Letters, 2019
A novel palladium-catalyzed interannular selective C-H silylation of 1,1'-biaryl-2-acetamides is described. The combination of palladium catalyst with copper oxidant enables meta- or ortho-selective C-H silylation by employing hexamethyldisilane as a ...
Wenguang Li, Wenqi Chen, Bang Zhou, Yankun Xu, Guobo Deng, Yun Liang, Yuan-Liang Yang   +6 more
semanticscholar   +1 more source

C-Glycosylation enabled by N-(glycosyloxy)acetamides.

Organic and biomolecular chemistry, 2020
The C-glycosylation of C-nucleophiles including allyltrimethylsilane, silyl enol ethers and phenols with N-(glycosyloxy)acetamides as glycosyl donors has been realized.
Miao Liu, Bohan Li, Tian Li, Xia Wu, Meng Liu, Decai Xiong, X. Ye   +6 more
semanticscholar   +1 more source

BF3·OEt2 Catalyzed Vinyl Azides Addition to in situ Generated N-Acyl Iminium Salts: Synthesis of 3-Oxoisoindoline-1-acetamides.

Journal of Organic Chemistry, 2019
BF3·OEt2 catalyzed nucleophilic addition of vinyl azide towards in situ generated N-acyl iminium salts obtained from 3-hydroxyisoindolinones has been described in this manuscript. The procedure is operationally simple, mild, additive and metal free.
Deb Kumar Das, Vinod K Kannaujiya, Milon M. Sadhu, Sumit Ray, V. Singh   +4 more
semanticscholar   +1 more source

Copper/B2pin2-Catalyzed Difluoroalkylation of Methylenecyclopropanes with Bromodifluorinated Acetates and Acetamides: One-pot Synthesis of CF2-Containing Dihydronaphthalene Derivatives.

Journal of Organic Chemistry, 2019
A novel copper/B2pin2-catalyzed difluoroalkylation of methylenecyclopropanes with bromodifluorinated acetates and acetamides via tandem radical process involving ring-opening/intramolecular cyclization has been reported.
Chuan Liu, Yan-Jie Yang, Junfang Dong, Mingxia Zhou, Lei Li, He Wang   +5 more
semanticscholar   +1 more source

Synthesis of 2‐(2‐oxo‐2H‐chromen‐4‐yl)acetamides as potent acetylcholinesterase inhibitors and molecular insights into binding interactions

Archiv der Pharmazie, 2019
Sixteen novel coumarin‐based compounds are reported as potent acetylcholinesterase (AChE) inhibitors. The most active compound in this series, 5a (IC50 0.04 ± 0.01 µM), noncompetitively inhibited AChE with a higher potency than tacrine and galantamine ...
Jiraporn Kara, Paptawan Suwanhom, C. Wattanapiromsakul, T. Nualnoi, J. Puripattanavong, P. Khongkow, V. Lee, Anand Gaurav, Luelak Lomlim   +8 more
semanticscholar   +1 more source