Results 291 to 300 of about 319,390 (394)

Development of CPA‐Catalyzed β‐Selective Reductive Amination of Cardenolides for the Synthesis and Biological Evaluation of Hydrolytically Stable Analogs

Chemistry – A European Journal, Volume 31, Issue 41, July 22, 2025.
We describe a new method to produce hydrolytically stable cardiotonic steroids using a CPA‐controlled diastereoselective reductive amination of cardenolide aglycones. The oleandrin and digitoxigenin analogs exhibited promising activity against various cancer cell lines in the NCI‐60 screen.
Natasha Perry, Shehab Eid, Gerold Schmitt‐Ulms, Pavel Nagorny   +3 more
wiley   +1 more source

Sustainable Agriculture Solutions: Biodegradable Coatings for Enhanced-Efficiency Fertilizers Using Cellulose and Lignin. [PDF]

J Agric Food Chem
Boberski P, Główka M, Torchała K, Kulczycki G, Kuźnik N.   +4 more
europepmc   +1 more source

Solvent-Based Recycling as a Waste Management Strategy for Fibre-Reinforced Polymers: Current State of the Art. [PDF]

Polymers (Basel)
Keith MJ, Al-Duri B, McDonald TO, Leeke GA.   +3 more
europepmc   +1 more source

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium Tuberculosis: Progress Toward Novel Antitubercular Agents

ChemMedChem, Volume 20, Issue 14, July 18, 2025.
A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Sanderson D. Calixto, Juliane S. Falcão, Stella S. Antunes, Marlon H. Araujo, Alexandre L. B. Cunha, David R. Martins, Sarah M. R. Nascimento, Thatiana L. B. V. Simão, Elena B. Lasunskaia, Nelilma C. Romeiro, Paulo R. R. Costa, Michelle F. Muzitano, Guilherme S. Caleffi   +12 more
wiley   +1 more source

Development of a Photocrosslinkable Collagen-Bone Matrix Hydrogel for Bone Tissue Engineering. [PDF]

Polymers (Basel)
Chen PH, Tsai WB.
europepmc   +1 more source

Molecular Fragmentation as a Strategy to Access Hyperpolarized Compounds from Para‐Hydrogen

ChemPhysChem, Volume 26, Issue 14, July 18, 2025.
Hyperpolarization using para‐hydrogen is a simple and cost‐effective method to dramatically increase sensitivity in magnetic resonance. When combined with chemical reactions that generate smaller fragments, a much wider array of different hyperpolarized molecules can be accessed.
Philip L. Norcott
wiley   +1 more source

Design and synthesis of polymer nanoparticles with pH-responsive pan-HDAC inhibitor (C5) derived from norbornene block copolymers to increase C5 solubility and improve its targeted delivery to prostate cancer sites. [PDF]

J Enzyme Inhib Med Chem
Mathew J, Mishra A, Le TN, Liou JP, Lai MJ, Rao Neralla V.   +5 more
europepmc   +1 more source

Sustainable Approaches for the Protection and Deprotection of Functional Groups

Chemistry – A European Journal, Volume 31, Issue 40, July 17, 2025.
Shield: Protection and deprotection are key to selective synthesis, but conventional methods can lack sustainability. This review highlights electrochemical and photochemical strategies as greener alternatives, emphasizing their mechanisms, functional group tolerance, and broad synthetic utility.
Ju Ha Jin, Mina An, Minki Jeon, Jaejeong Kim, Sung Min Kang, Isaac Choi   +5 more
wiley   +1 more source

Micromolar Concentration Affinity Study on a Benchtop NMR Spectrometer with Secondary ¹³C Labeled Hyperpolarized Ligands. [PDF]

ACS Omega
Cala O, Bocquelet C, Gioiosa C, Torres F, Cousin SF, Guibert S, Ceillier M, Busse V, Decker F, Kempf JG, Elliott SJ, Stern Q, Bornet A, Jannin S.   +13 more
europepmc   +1 more source

Nutritionally Responsive PMv DAT Neurons Are Dynamically Regulated During Pubertal Transition

The FASEB Journal, Volume 39, Issue 13, 15 July 2025.
The ventral premammillary nucleus of the hypothalamus plays an essential role in the metabolic control of reproduction. Puberty brings large changes to a subpopulation of PMvLepRb cells expressing the dopamine transporter (PMvDAT). DAT gene expression is higher in prepubertal females than in adults and is regulated by leptin in prepubertal females ...
Cristina Sáenz de Miera, Nicole Bellefontaine, Marina A. Silveira, Chelsea N. Fortin, Thais T. Zampieri, Jose Donato Jr, Kevin W. Williams, Cristiano Mendes‐da‐Silva, Laura Heikkinen, Christian Broberger, Renata Frazao, Carol F. Elias   +11 more
wiley   +1 more source