Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15-Veratroyl-17-Acetyl-19-Oxodictizine, and the Proposed Structure of Acochlearine. [PDF]
An intramolecular Mannich reaction (A/B/E/F rings) and intermolecular Diels–Alder reactions (C/D rings) afforded a cage‐like hexacyclic core skeleton of denudatine alkaloids. Derivatization of the hexacyclic intermediate enabled the first asymmetric total syntheses of four denudatine alkaloids: (–)‐cochlearenine, (–)‐macrocentrine, (–)‐dictizine, and (–
Kawano S +5 more
europepmc +3 more sources
Highly-functionalised difluorinated cyclohexane polyols via the Diels–Alder reaction : regiochemical control via the phenylsulfonyl group [PDF]
A difluorinated dienophile underwent cycloaddition reactions with a range of furans to afford cycloadducts whichcould be processed regio- and stereoselectively via episulfonium ions, generated by the reaction between their alkenyl groups and ...
Crowley, Patrick J +5 more
core +1 more source
Objective To evaluate the efficacy of the local injection of Salvia miltiorrhiza combined with triamcino⁃ lone acetonide and triamcinolone acetonide alone in the treatment of oral submucous fibrosis (OSF).
LIU Gui +3 more
doaj +1 more source
The Relative Effects of Monotherapies for Psoriatic Nails: A Network Meta-Analysis Study. [PDF]
ABSTRACT Background Various treatments exist for nail psoriasis (NP). We determined the relative efficacy of various monotherapies through Bayesian network meta‐analyses (NMAs). Methods We systematically reviewed the literature to identify eligible studies which—within the patient, intervention, comparator, outcome (PICO) context—determined the impact ...
Gupta AK +3 more
europepmc +2 more sources
Some forms of triamcinolone may provide alternate options for local therapy of the inner ear in addition to the steroids currently in use. We compared the perilymph pharmacokinetics of triamcinolone-acetonide, triamcinolone, and dexamethasone, each ...
Alec Nicholas Salt +3 more
doaj +1 more source
Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J +33 more
core +1 more source
The data presented in this article describe the physical state of the triamcinolone acetonide (TA) in nanosuspension stabilized with polyvinyl alcohol (PVA) and poloxamer 407 (PL).
Eva GarcÃa-Millán +2 more
doaj +1 more source
The influence of intravitreally applied triamcinolone acetonide on vitreal hemorrhage resorption and visual acuity in patients with proliferative diabetic retinopathy [PDF]
Introduction/Objective. Vitreal hemorrhage (VH) is one of the possible complications of the diabetic retinopathy which is followed by intensive decrease of visual acuity.
Petrović Nenad +7 more
doaj +1 more source
This work aims to study the qualitative composition of biologically active substance (BAS) extracts in vitro callus, cell suspension, and root cultures of the medicinal plant Rhaponticum carthamoides. The research methodology is based on high-performance
Lyudmila Asyakina +7 more
doaj +1 more source
Comparison between “early” or “late” intravitreal injection of dexamethasone implant in branch (BRVO) or central (CRVO) retinal vein occlusion: six months follow-up [PDF]
AIM: The aim of this study was to compare early and late injections of intravitreal dexamethasone implant in patients affected by central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) with a six-months follow-up.
AUTOLITANO, MONICA +6 more
core +1 more source

