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Teratogenicity of triamcinolone acetonide in rats
Teratology, 1983AbstractThe objective of this investigation was to study the teratogenic effects of triamcinolone acetonide (TAC) in the rat. Pregnant females were injected intramuscularly once each day for three consecutive days (days 9–11, 12–14, or 15–17 of gestation) either with vehicle alone or with 0.125, 0.25, or 0.5 mg/kg TAC.
Andrew G Hendrickx, J. M. Rowland
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Journal of Ocular Pharmacology and Therapeutics, 2018
PURPOSE To achieve a safer alternative to intravitreal injection of corticosteroids, we developed and characterized triamcinolone acetonide-loaded liposomes formulations (TA-LFs) to be used topically for vitreoretinal drug delivery.
J. C. Altamirano-Vallejo +8 more
semanticscholar +1 more source
PURPOSE To achieve a safer alternative to intravitreal injection of corticosteroids, we developed and characterized triamcinolone acetonide-loaded liposomes formulations (TA-LFs) to be used topically for vitreoretinal drug delivery.
J. C. Altamirano-Vallejo +8 more
semanticscholar +1 more source
The Clearance of Intravitreal Triamcinolone Acetonide
American Journal of Ophthalmology, 1982Since high corticosteroid levels are important in achieving inhibition of intraocular cellular proliferation, we studied the clearance of an intravitreally injected slowly dissolving corticosteroid in the rabbit eye. Triamcinolone acetonide (0.5 mg) disappeared rapidly in eyes that underwent a combined vitrectomy and lensectomy (average, 6.5 days) and ...
Randy Thresher +3 more
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Fluocinolone Acetonide Intravitreal Implant 0.19 mg (ILUVIEN®): A Review in Diabetic Macular Edema
Drugs, 2017Peter A G M De Smet, Zheng Lu
exaly +2 more sources
Solubility and Dissolution of Triamcinolone Acetonide
Journal of Pharmaceutical Sciences, 1973Available data on the solubility of triamcinolone acetonide in aqueous media are neither complete nor in agreement. Solubility of the steroid in distilled water and in potassium chloride solutions of varying ionic strength was determined at 28, 37, and 50°. Dissolution rates of the steroid in the aqueous media were determined at 28° via a rotating‐disk
Lawrence H. Block, R.N. Patel
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An Efficient and Selective Method for Hydrolysis of Acetonides [PDF]
Synlett, 2001 AbstractFor Abstract see ChemInform Abstract in Full Text.
Xiangshu Xiao, Donglu Bai
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Oral Surgery, Oral Medicine, Oral Pathology, 1960
Abstract The effects of the application of triamcinolone acetonide (Kenalog) 0.1 per cent in an adhesive ointment to the oral mucosa of the rat for ten days were studied with regard to weight gain, adrenal and testicular weights, and gross and histologic examination of the internal organs. The administration of 0.06 mg.
Werner Dutz +7 more
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Abstract The effects of the application of triamcinolone acetonide (Kenalog) 0.1 per cent in an adhesive ointment to the oral mucosa of the rat for ten days were studied with regard to weight gain, adrenal and testicular weights, and gross and histologic examination of the internal organs. The administration of 0.06 mg.
Werner Dutz +7 more
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Journal of Cosmetic Dermatology, 2018
This study aims to clarify whether the effect of intralesional triamcinolone acetonide injection during the early stage of scarring differs from the static stage, which still remains unclear.
Huapei Song +4 more
semanticscholar +1 more source
This study aims to clarify whether the effect of intralesional triamcinolone acetonide injection during the early stage of scarring differs from the static stage, which still remains unclear.
Huapei Song +4 more
semanticscholar +1 more source
Trans-Scleral Diffusion of Triamcinolone Acetonide
Current Eye Research, 2005To assess ex vivo human scleral permeability to triamcinolone acetonide (TA).The experiments were carried out using scleral samples and a Franz-type vertical diffusion cell. A suspension containing TA was prepared and placed in the donor chamber. The concentration of TA in the receptor chamber was measured by high-performance liquid chromatography ...
MORA, Paolo +6 more
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Photochemistry and Phototoxicity of Fluocinolone 16,17-Acetonide¶
Photochemistry and Photobiology, 2004ABSTRACTFluocinolone 16,17‐acetonide is a corticosteroid used topically to treat various inflammatory skin diseases. Its photoreactivity was studied under UV‐A and UV‐B light in aqueous buffer in the presence of oxygen. This drug is photolabile under UV‐B light and, to a lesser extent, under UV‐A light, which is absorbed far less.
MIOLO, GIORGIA +5 more
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