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Diabetic macular edema is the most common cause of vision loss in patients affected by diabetes mellitus. For eyes with persistent retinal thickening despite anti-VEGF therapy, treatment with intravitreal triamcinolone may be considered, especially in ...
Nenad Petrović+6 more
doaj +1 more source
The synthesis of(–)-5-[(4R,5R)-5-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-4,7-dihydro-1,3-dioxepine is reported. Product characterization was carried out by IR, 1H NMR, 13C NMR, MS, elemental analysis and optical rotation.
Carlos R. Carreras+5 more
doaj +1 more source
Corticosteroid implants for chronic non-infectious uveitis. [PDF]
BACKGROUND: Uveitis is a term used to describe a heterogeneous group of intraocular inflammatory diseases of the anterior, intermediate, and posterior uveal tract (iris, ciliary body, choroid).
Brady, Christopher J+7 more
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Ecdysteroids, molting hormones of insects, can exert several mild, non-hormonal bioactivities in mammals, including humans. In a previous study, we have found a significant effect of certain derivatives on the ABCB1 transporter mediated multi-drug ...
Ana Martins+8 more
doaj +1 more source
Introduction: The ILUVIEN ® (fluocinolone acetonide) Clinical Evidence in Portugal (ICE-PT) study is a retrospective, multicenter, observational study evaluating the effectiveness and safety of the FAc implant in patients with diabetic macular edema ...
Angela Carneiro+3 more
doaj +1 more source
Widening use of dexamethasone implant for the treatment of macular edema [PDF]
Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis.
Avitabile T.+9 more
core +2 more sources
Objective To evaluate the efficacy of the local injection of Salvia miltiorrhiza combined with triamcino⁃ lone acetonide and triamcinolone acetonide alone in the treatment of oral submucous fibrosis (OSF).
LIU Gui+3 more
doaj +1 more source
The inflammatory process of gout and its treatment. [PDF]
Gouty arthritis is a characteristically intense acute inflammatory reaction that erupts in response to articular deposits of monosodium urate (MSU) crystals.
Cronstein, Bruce N, Terkeltaub, Robert
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Introduction: Transepidermal drug delivery, using “laser-assisted drug delivery'', or microneedling, are new treatment modalities, that can improve drug penetration into skin in treatment of alopecia areata patients. Objective: To evaluate the use of
Khaled El Mulla+3 more
doaj +1 more source
Highly-functionalised difluorinated cyclohexane polyols via the Diels–Alder reaction : regiochemical control via the phenylsulfonyl group [PDF]
A difluorinated dienophile underwent cycloaddition reactions with a range of furans to afford cycloadducts whichcould be processed regio- and stereoselectively via episulfonium ions, generated by the reaction between their alkenyl groups and ...
Crowley, Patrick J+5 more
core +1 more source