Results 51 to 60 of about 45,721 (281)
Synthesis and RP-TLC lipophilicity evaluation of a novel fluocinolon acetonide soft drug derivative [PDF]
Kragujevac Journal of Science, 2016 Cortienic acid was obtained by periodic acid oxidation of fluocinolone acetonide, whereas corresponding amide was synthesized from the cortienic acid and ethyl ester of b-alanine by dicyclohexylcarbodiimide - hydroxybenzotriazole coupling procedure ...
Dobričić Vladimir +2 more
doaj +1 more source
Journal of Indian Academy of Oral Medicine and Radiology, 2022 Introduction: Recurrent aphthous stomatitis (RAS) is the most common oral mucosal disease known to humans and are characterized by the development of painful, recurring solitary or multiple ulcers confined to the oral mucosa.
Amit A Mhapuskar +5 more
doaj +1 more source
Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
, 2011 Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Przybilla, Bernhard +3 more
core +1 more source
Towards conformationally-locked difluorosugar analogues : an unexpected sense of dihydroxylation [PDF]
, 2004 Difluorinated cyclooctenones, synthesised using RCM, can be used as templates for stereoselective oxidative transformations to products that undergo transannular reactions to afford conformationally-locked analogues of 2-deoxy-2,2-difluorosugars with ...
Fawcett, John +6 more
core +1 more source
Journal of International Medical Research, 2018 Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy and may lead to severe visual loss. In this review, we describe the pathophysiology of DMO and review current therapeutic options such as macular laser photocoagulation, anti ...
H. Massa +5 more
semanticscholar +1 more source
Microneedles at the Forefront of Next Generation Theranostics
Advanced Science, EarlyView.The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang +8 more
wiley +1 more source
Rheumatology, 2018 Objective Approximately 30% of patients with type 2 diabetes mellitus have knee osteoarthritis. IA corticosteroids used to manage osteoarthritis pain can elevate blood glucose in these patients.
S. Russell +11 more
semanticscholar +1 more source
Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]
, 2005 Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Ahmed, M. +4 more
core +1 more source
Angewandte Chemie International Edition, Accepted Article.Pseudouridine‐5’‐triphosphate (ΨTP) and the N1‐methylated derivative (m1ΨTP) are critical monomer building blocks of the currently used mRNA vaccines, yet efficient methods of their synthesis from readily accessible substrates remain underdeveloped. We herein report notably atom‐economic and high‐yielding biocatalytic route toward ΨTP (83% yield) and ...
Martin Pfeiffer +4 more
wiley +1 more source
Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates. [PDF]
, 2020 Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery and ...
Chung, Sook Hyun +7 more
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