Results 81 to 90 of about 31,826 (289)

2-C-Cyclohexyl-2,3-O-isopropylideneerythrofuranose

open access: yesActa Crystallographica Section E, 2009
In the title compound, C13H22O4, the acetonide ring adopts an envelope conformation with one of the O atoms as the flap atom, whereas a twisted conformation is found for the furanose ring.
Edward R. T. Tiekink   +2 more
doaj   +1 more source

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano   +8 more
wiley   +1 more source

The Efficacy of Triamcinolone Acetonide in Keloid Treatment: A Systematic Review and Meta-analysis

open access: yesFrontiers in Medicine, 2016
Keloid is a cutaneous dermal outgrowth resulting from uncontrolled deposition of collagen and glycosaminoglycan around the wound. The uncontrolled and persistent growth of keloids scar will result in cosmetic disfigurement, functional impairment, and ...
T. Wong   +4 more
semanticscholar   +1 more source

Factors associated with visual recovery after sub-Tenon injection of triamcinolone acetonide in diabetic macular edema

open access: yesClinical Ophthalmology, 2012
Hiroko Kawashima, Kenichi Mizukawa, Junichi KiryuDepartment of Ophthalmology, Kawasaki Medical School, Okayama, JapanBackground: The purpose of this retrospective chart review was to evaluate factors associated with improvement of visual acuity after a ...
Kawashima H, Mizukawa K, Kiryu J
doaj  

Drug Delivery Implants in the Treatment of Vitreous Inflammation

open access: yesMediators of Inflammation, 2013
The eye is a model organ for the local delivery of therapeutics. This proves beneficial when treating vitreous inflammation and other ophthalmic pathologies.
Jillian Wang   +3 more
doaj   +1 more source

Prevention of posterior capsular opacity after pediatric cataract surgery

open access: yesDelta Journal of Ophthalmology, 2018
Objective The objective of this article is to evaluate the effect of triamcinolone acetonide and enoxaparin on prevention of posterior capsule opacification (PCO) after pediatric cataract surgery Patients and methods A total of 44 eyes of 34 patients ...
Ahmed H Aldghaimy   +2 more
doaj   +1 more source

Synthesis of Diverse β,β‐Diaryl β‐Siloxy Diamines and Application as Organocatalysts

open access: yesEuropean Journal of Organic Chemistry, Accepted Article.
β,β‐Diaryl‐β‐siloxy diamines were developed as a tunable scaffold for structurally diverse diamine‐based organocatalysts. Synthesis was initiated with the reaction of an oxazolidine methyl ester from L‐serine with various Grignard reagents, introducing a wide range of diaryl substituents at the β‐position.
Satoru Arimitsu   +3 more
wiley   +1 more source

Synthesis of Bioorthogonal Mycolic Acids: Chemoselective Reduction of β‐Ketoesters Containing an Alkyne Using the Noyori Catalyst

open access: yesEuropean Journal of Organic Chemistry, Accepted Article.
The asymmetric reduction of β‐ketoesters using the Noyori catalyst is a highly effective synthetic methodology, offering excellent stereocontrol for the preparation of enantiopure b‐hydroxyesters from prochiral substrates in high yields. This reaction has been used in the total synthesis of mycolic acids, which are α‐alkyl, β‐hydroxy fatty acids ...
Paulin Rollando   +5 more
wiley   +1 more source

Endoscopic remodeling of esophageal stenosis refractory to traditional endoscopic treatment

open access: yesJPGN Reports, EarlyView.
Abstract Esophageal atresia (EA), with or without tracheoesophageal fistula, is the most common congenital anomaly of the esophagus. Surgical correction is the primary treatment, however, up to 80% of patients experience anastomotic stenosis, with esophageal balloon dilation (EBD) being the first‐line treatment.
María Camila Beltrán‐Ramírez   +2 more
wiley   +1 more source

Polyamidoamine dendrimer-conjugated triamcinolone acetonide attenuates nerve injury-induced spinal cord microglia activation and mechanical allodynia

open access: yesMolecular Pain, 2017
Background Accumulating evidence on the causal role of spinal cord microglia activation in the development of neuropathic pain after peripheral nerve injury suggests that microglial activation inhibitors might be useful analgesics for neuropathic pain ...
H. Kim   +8 more
semanticscholar   +1 more source

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