Results 271 to 280 of about 374,029 (398)

DON‐Loaded Nanodrug‐T Cell Conjugates With PD‐L1 Blockade for Solid Tumor Therapy

Advanced Science, EarlyView.
This study establishes DON‐loaded T cell‐nanodrug conjugates with PD‐L1 blockade, creating a synergistic system. As a glutamine antagonist, sustained DON release enhances T‐cell endurance and infiltration by promoting memory differentiation and upregulating adhesion and motility genes, while PD‐L1 blockade alleviates immunosuppression and directs T ...
Xin Yang, Xiaoshuang Niu, Ye Su, Xiaoyun Ye, Wanqiong Li, Wenxuan Zeng, Xin Zhao, Zhuoying He, Qingyu Dong, Xiuman Zhou, Xinghua Sui, Guanyu Chen, Yanfeng Gao, Juan Liu   +13 more
wiley   +1 more source

Post-translational modifications and the reprogramming of tumor metabolism. [PDF]

Discov Oncol
Hu Y, Xu W, Chen L.
europepmc   +1 more source

Effect of histone acetylation on structure and in vitro transcription of chromatin [PDF]

, 1978
Diane Mathis, P Oudet, Bohdan Wasylyk, Pierre Chambon   +3 more
openalex   +1 more source

High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

Advanced Science, EarlyView.
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti, Linda Popella, Jörg Vogel, Hans M. Maric   +3 more
wiley   +1 more source

Dehydrodiisoeugenol alleviates palmitate-induced mitochondrial dysfunction in human vascular smooth muscle cells through the activation of SIRT1-mediated Drp1 deacetylation. [PDF]

Lipids Health Dis
Zhao J, Shu Z, Li X, Zhang W, Sun M, Song W, Cheng H, Shi S.   +7 more
europepmc   +1 more source

The Enzymatic Acetylation of Chloramphenicol by Extracts of R Factor-resistant Escherichia coli

, 1967
William V. Shaw
openalex   +1 more source

MdDSK2a‐Like‐MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition

Advanced Science, EarlyView.
Under cold stress, MdDSK2a‐like is degraded via the 26S proteasome pathway, thereby alleviating the degradation of MdMTA induced by the 26S proteasome and autophagy pathways mediated by MdDSK2a‐like. The accumulated MdMTA increases the m6A levels of cold‐responsive genes, thereby contributing to increased ROS detoxification, deposition of cell wall, as
Nan Hou, Jieqiang He, Chana Bao, Fang Zhi, Xiaoxia Shen, Yu Liu, Chaoshuo Li, Tianle Fan, Xinyue Yang, Baohua Chu, Gege Qin, Zeyuan Liu, Chuang Mei, Bin Tan, Jiancan Feng, Fengwang Ma, Mickael Malnoy, Xuewei Li, Qingmei Guan   +18 more
wiley   +1 more source

The mammalian longevity associated acetylome. [PDF]

Nat Commun
Feldman-Trabelsi S, Touitou N, Nagar R, Schwartz Z, Michelson A, Shaki S, Avivi MY, Lerrer B, Snir S, Cohen HY.   +9 more
europepmc   +1 more source

Acetylation of Amino and Tyrosine Hydroxyl Groups

, 1967
Derek G. Smyth
openalex   +1 more source

Enzymatic N-acetylation of indolealkylamines by brain homogenates of the honeybee, Apis mellifera [PDF]

, 1975
Philip Evans, Patricia Fox
openalex   +1 more source