Radiolabeling of proteins and viruses in vitro by acetylation with radioactive acetic anhydride.
, 1975 Ronald C. Montelaro, Roland R. Rueckert
openalex +1 more source
Large‐Scale Chemoenzymatic Synthesis of a Glycophorin A Tetrasaccharide Motif and Its Analogues
Asian Journal of Organic Chemistry, EarlyView.A large‐scale chemoenzymatic method was developed to synthesize natural and modified analogues of the Glycophorin A tetrasaccharide with either C9 or C5 terminal α‐2,3‐sialic acid variants. Selective α‐2,6‐sialylation of galactosamine was achieved by maintaining acetylation of the galactose during the course of enzymatic reactions. The products can aid
Ivan A. Gagarinov +5 more
wiley +1 more source
Post-translational modifications orchestrate mTOR-driven cell death in cardiovascular disease. [PDF]
Front Cardiovasc MedGuo J, Wu Y, Wan Z, Zhang Z.
europepmc +1 more source
Synthesis of 1‐Naphthylamines Utilizing [4 + 2] Cycloaddition Between 3‐Amino‐2‐pyrones and Benzynes
Asian Journal of Organic Chemistry, EarlyView.Synthesis of 1‐naphthylamines is developed using [4 + 2] cycloaddition between 3‐amino‐2‐pyrone, which is prepared by the conjugate addition reaction of diethyl 2‐aminomalonate to alkynyl ketones, and benzyne generated from o‐silylaryl triflates. This synthetic strategy was successfully applied to the syntheses of iodonaphthalene, naphthylimide, and ...
Atsuya Kawazoe +2 more
wiley +1 more source
Chirality Makes or Breaks Chemically Driven Self‐Assembly
Angewandte Chemie, EarlyView.Chirality‐controlled reaction cycles: Reaction cycles are constructed to respond to the chirality (handedness) of an acylating agent. Left‐ and right‐handed aminoacyl phosphate esters modulate the structure, lifetime, and transformation of transient (thio)ester intermediates, enabling control over distinct chemical pathways using molecules that are ...
Lenard Saile +5 more
wiley +2 more sources
Chronic Alcohol Consumption Reprograms Hepatic Metabolism Through Organelle-Specific Acetylation in Mice. [PDF]
Mol Cell ProteomicsAghayev M +10 more
europepmc +1 more source
Advanced NanoBiomed Research, EarlyView.A neuron‐targeting drug delivery system is developed by incorporating the tau‐specific N‐amino peptide, mxyl‐NAP2, with graphene quantum dots (GQDs) and encapsulating the complex into small extracellular vesicles functionalized with a neuron‐targeting ligand.
Runyao Zhu +5 more
wiley +1 more source
Backbone Protecting Groups for Enhanced Peptide and Protein Synthesis
Angewandte Chemie, EarlyView.This review provides a comprehensive account of the use of backbone N‐protecting groups in peptide synthesis. It includes detailed synthetic methods relating to their introduction and removal and their application to “difficult” peptides and proteins of biological significance in both academic and industry contexts.
Samuel J. Paravizzini +3 more
wiley +2 more sources
Acetylation-induced degradation of ECHS1 enhances BCAA accumulation and proliferation in KRAS-mutant colorectal cancer. [PDF]
J Exp Clin Cancer ResLi Z +13 more
europepmc +1 more source
Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation
Advanced NanoBiomed Research, EarlyView.Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos +2 more
wiley +1 more source