Results 311 to 320 of about 343,067 (338)
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Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1975
a-Bungarotoxin is one of a class of proteins, isolated from snake venoms, which antagonize the action of acetylcholine at vertebrate neuromuscular junctions and ‘electroplaques' of electric fish. a-Bungarotoxin blocks acetylcholine action irreversibly and may be labelled with either 125 I or 3
D P, Green +3 more
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a-Bungarotoxin is one of a class of proteins, isolated from snake venoms, which antagonize the action of acetylcholine at vertebrate neuromuscular junctions and ‘electroplaques' of electric fish. a-Bungarotoxin blocks acetylcholine action irreversibly and may be labelled with either 125 I or 3
D P, Green +3 more
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Nature, 1965
THE development of the attenuated total reflexion (ATR) method1,2 for the examination of aqueous solutions in the infra-red region has made it possible to re-examine the problem of the conformation of acetylcholine (Ach) in aqueous and mammalian Ringer solution.
F G, Canepa, E F, Mooney
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THE development of the attenuated total reflexion (ATR) method1,2 for the examination of aqueous solutions in the infra-red region has made it possible to re-examine the problem of the conformation of acetylcholine (Ach) in aqueous and mammalian Ringer solution.
F G, Canepa, E F, Mooney
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Conformations of Acetylcholine
Nature, 1968Canepa, Pauling and Sorum1 have reported the single crystal structure analysis of acetylcholine bromide and pointed out a correlation between that structure and those of choline chloride and muscarine iodide. In particular the (CH3)3N+–C–C–O– groups of all three are very similar in conformation with the ether oxygen atom gauche to the nitrogen atom ...
C, Chothia, P, Pauling
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Nature, 1958
ACETYLCHOLINE has recently been reported to be present in low concentrations (0.1–1 µgm./ml.) in the milk of various species1–4. On the other hand, the mammary gland does not appear to possess a cholinergic innervation5,6. Accordingly, the question of the presence of acetylcholine in milk has been re-examined.
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ACETYLCHOLINE has recently been reported to be present in low concentrations (0.1–1 µgm./ml.) in the milk of various species1–4. On the other hand, the mammary gland does not appear to possess a cholinergic innervation5,6. Accordingly, the question of the presence of acetylcholine in milk has been re-examined.
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Acetylcholine Binding Site in the Vesicular Acetylcholine Transporter
Biochemistry, 2004This study sought primarily to locate the acetylcholine (ACh) binding site in the vesicular acetylcholine transporter (VAChT). The design of the study also allowed us to locate residues linked to (a) the binding site for the allosteric inhibitor vesamicol and (b) the rates of the two transmembrane reorientation steps of a transport cycle.
Ana M, Ojeda +2 more
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Action of acetylcholine on rabbit auricles in relation to acetylcholine synthesis
The Journal of Physiology, 1949WHEN the heart is removed from a freshly killed rabbit, the auricles can be dissected and put in a bath of Tyrode solution at 28° C. in which they continue to beat. The addition of acetylcholine to the bath slows the rate and diminishes the amplitude of the contractions.
E, BULBRING, J H, BURN
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Acta Physiologica Scandinavica, 1951
Summary.In the non‐atropinized cat small doses of acetylcholine stimulate respiration practically only by lowering the blood pressure, thereby causing local oxygen want within the carotid and aortic bodies. With somewhat larger doses (0.2 mg) there is also a direct stimulation of the chemoreceptors as well as an inhibition of the centre and a ...
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Summary.In the non‐atropinized cat small doses of acetylcholine stimulate respiration practically only by lowering the blood pressure, thereby causing local oxygen want within the carotid and aortic bodies. With somewhat larger doses (0.2 mg) there is also a direct stimulation of the chemoreceptors as well as an inhibition of the centre and a ...
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Nature, 1953
A STUDY of two species of blowfly, Calliphora erythrocephala and Lucilia sericata, has shown that a rapid synthesis of an acetylcholine-like substance can take place in extracts prepared from these insects. This synthesis, which occurs in the absence of additional substrate, may account for some of the high concentrations of acetylcholine which have ...
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A STUDY of two species of blowfly, Calliphora erythrocephala and Lucilia sericata, has shown that a rapid synthesis of an acetylcholine-like substance can take place in extracts prepared from these insects. This synthesis, which occurs in the absence of additional substrate, may account for some of the high concentrations of acetylcholine which have ...
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Quarterly Reviews of Biophysics, 1974
The idea that certain drugs and neurotransmitters produce their effects by combining with specific receptors was first clearly expressed by Langley (1905) on the basis of the selective and localized effect of nicotine on striated muscle fibres. In 1914, Langley published a paper in which the antagonism between ‘curari’ and nicotine ...
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The idea that certain drugs and neurotransmitters produce their effects by combining with specific receptors was first clearly expressed by Langley (1905) on the basis of the selective and localized effect of nicotine on striated muscle fibres. In 1914, Langley published a paper in which the antagonism between ‘curari’ and nicotine ...
openaire +2 more sources