Results 111 to 120 of about 60,876 (204)
Abstract Neurons depend on tightly regulated spatial proteostasis to maintain function across their extended morphology. The endoplasmic reticulum (ER), traditionally known for its function in protein synthesis, folding, and trafficking, has long been recognized as a central platform for directing proteins to organelles of the secretory and endocytic ...
J. Tabitha Hees, Angelika B. Harbauer
wiley +1 more source
In Silico Structural Analysis of Human β‐Glucuronidase for Antibody–Drug Conjugates Optimization
ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Giorgia Canini +5 more
wiley +1 more source
A Comprehensive Study of Piezoelectricity in Chitosan Films
This work explores the correlation between crystallinity and piezoelectricity in solution‐cast chitosan films with respect to their fabrication process, giving a final recipe allowing to reach a d33 = 27 pm V−1, nearly twice as high as those previously reported in the literature.
Sofia Papa +7 more
wiley +1 more source
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak +7 more
wiley +1 more source
A network-based analysis of bacterial growth on substrate mixtures uncovers glucose inhibition in Phaeobacter inhibens. [PDF]
Lücken L, Blasius B.
europepmc +1 more source
Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments
ABSTRACT Biofilms formed by mycobacteria, particularly Mycobacterium tuberculosis (Mtb), represent a major challenge in tuberculosis (TB) treatment due to their highly organized structure and their capacity to induce phenotypic drug tolerance. These three‐dimensional bacterial aggregates are embedded in a self‐produced extracellular matrix that ...
Lourdes Serrano Garcia +3 more
wiley +1 more source
O-Linked N-Acetylglucosamine Epitope H Expression in Placentas of Pregnancies Complicated With Fetal Growth Restriction: A Case-Control Immunochemistry Study. [PDF]
Karkabouna A +6 more
europepmc +1 more source
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk +8 more
wiley +1 more source
N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens. [PDF]
Shamoon Naseem, James B Konopka
doaj +1 more source

