Results 271 to 280 of about 124,541 (336)

Repurposing Acetylcholinesterase Inhibitors for Leishmaniasis: Donepezil Hydrochloride and Related Compounds Against the American Tegumentary Form. [PDF]

Antibiotics (Basel)
Barraza DE, Araoz EN, Occhionero MA, Gaspar DA, Guevara EG, Vázquez ME, Zabala BA, Barroso PA, Pérez Brandán C, Minahk CJ, Acuña L.   +10 more
europepmc   +1 more source

Plain Language Summary Publication: Efficacy and safety of rimegepant for the preventive treatment of migraine in Japan: A double‐blind, randomized controlled trial

Headache: The Journal of Head and Face Pain, EarlyView.
Shigekazu Kitamura, Yasuhiko Matsumori, Toshimasa Yamamoto, Tomofumi Ishikawa, Yuko Hoshino, Hiroki Yoshimatsu, Alexandra Thiry, Akio Arakawa, Robert Croop, Terence Fullerton, Fumihiko Sakai, Takao Takeshima   +11 more
wiley   +1 more source

Full‐length coding sequence analysis of the voltage‐gated sodium channel and acetylcholinesterase genes reveals target‐site mutations and acetylcholinesterase gene duplication in housefly (Musca domestica) populations in Japanese livestock barns

Medical and Veterinary Entomology, EarlyView.
We simultaneously analysed insecticide resistance mutations in VGSC and AChE using NGS and hybridization probe capture in houseflies collected from livestock facilities for the first time. Resistance mutations in both VGSC and AChE were detected in most wild populations, suggesting widespread distribution of resistance genes.
Mikie Nakagawa, Kentaro Itokawa, Nozomi Uemura, Yasuhiro Tomioka, Tsutomu Tanikawa, Kyo Itoyama, Shinji Kasai, Osamu Komagata   +7 more
wiley   +1 more source

Design, synthesis, and multi-target evaluation of 4-phenyl quinoline-8-sulfonate thiosemicarbazones as potential anti-Alzheimer agents. [PDF]

Sci Rep
Saeed R, Tariq HZ, Althobaiti A, Sadeghian N, Taslimi P, Al-Rashida M, Islam T, Thabet HK, Aftab H, Şenol H, Ameen M, Li J, Shafiq Z.   +12 more
europepmc   +1 more source

Effects of Yoga Nidra on Stress, Anxiety, and Depression: A Systematic Review and Meta‐Analysis

Annals of the New York Academy of Sciences, EarlyView.
ABSTRACT The global mental health crisis has escalated to unprecedented levels, with stress, anxiety, and depression posing major public health concerns. Conventional interventions have shown limited success in addressing these multifaceted issues, prompting researchers to explore alternative solutions.
Shashank Ghai, Pawel Odyniec, Ishan Ghai
wiley   +1 more source

Crystal Surface Reactivity of Esterase@Zeolitic Imidazolate Framework Biocomposites. [PDF]

J Am Chem Soc
Borrego-Marin E, López-Viseras ME, Martín-Romera JD, Vismara R, Carraro F, Falcaro P, Barea E, Navarro JAR.   +7 more
europepmc   +1 more source

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, EarlyView.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source

Structure-based design, synthesis, and biological activity evaluation of chalcone-piperazine derivatives as dual AChE and MAO B inhibitors. [PDF]

RSC Adv
Kurban B, Sağlık Özkan BN, Osmaniye D, Levent S, Özkay Y, Kaplancıklı ZA.   +5 more
europepmc   +1 more source

Crime Prevention Through Private Actors: Evidence From a Policy Change at a Large UK Supermarket Chain

Oxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT This paper investigates the effectiveness of private actors in contributing to crime prevention. We leverage well‐publicised increases in security measures, including additional security guards and tagging of goods, by Tesco, a large UK supermarket chain.
Nils Braakmann, Wednesday Croft
wiley   +1 more source