Results 91 to 100 of about 27,368 (256)

Optimizing the Straight Leg Raise Maneuver to Improve Prediction of Conclusive Gastro‐Esophageal Reflux Disease

Neurogastroenterology &Motility, EarlyView.
The SLR maneuver is a valuable component of GERD evaluation. By establishing optimal thresholds for both effective EGJ challenge and accurate GERD prediction, we provide another step for standardized implementation in clinical practice. ABSTRACT Background Gastroesophageal reflux disease (GERD) arises from dysfunction of the anti‐reflux barrier.
Stefano Siboni, Carlo Galdino Riva, Roberta De Maron, Marco Sozzi, Pierfrancesco Visaggi, Edoardo Savarino, Emanuele Asti, C. Prakash Gyawali   +7 more
wiley   +1 more source

The conundrum of esophagogastric junction outflow obstruction: Answers to key clinical questions

Annals of the New York Academy of Sciences, EarlyView.
Esophagogastric junction outflow obstruction (EGJOO) is a heterogeneous disorder characterized by abnormal esophagogastric junction pressures in the setting of intact peristalsis. The significance of this finding is highest in patients with dysphagia or chest pain, and in patients for whom there is a clinical suspicion for an achalasia variant.
Kristle Lee Lynch, C. Prakash Gyawali, Enrique Coss‐Adame, Stefano Siboni, Christopher Vélez, Abraham Khan, Pierfrancesco Visaggi, Joshua A. Sloan, Sravanya Gavini, Marco Sozzi, Justin Wu   +10 more
wiley   +1 more source

Achalasia and hyperthyroidism: A cooccurrence revealing autoimmune connections [PDF]

Romanian Medical Journal
Achalasia is a rare esophageal motility disorder characterized by an unknown etiology, myenteric inflammation, and autoimmune markers. We present a case of a 43-year-old female with progressive dysphagia, regurgitation, generalized weakness, and hair ...
Jibin Simon, K. V. Rajalakshmi, Ananthakumar P. K., Bhubaneswar, Sharan Bose   +4 more
doaj   +1 more source

A functional study of the esophagus in patients with non-cardiac chest pain and dysphagia [PDF]

, 2015
Background/Aims: Nutcracker esophagus and non-specific motility disorders are the main causes of non-cardiac chest pain (NCCP), with gastroesophageal reflux in 60% of cases. Achalasia and diffuse esophageal spasm are the most frequent anomalies described
ALMASIO, Pier Luigi, BONVENTRE, Sebastiano, DI GIOVANNI, Silvia, DI PAOLA, Valentina, GULLO, Roberto, GULOTTA, Gaspare, INVIATI, Angela, Scerrino, G.   +7 more
core   +1 more source

GEN-O-MA project: an Italian network studying clinical course and pathogenic pathways of moyamoya disease—study protocol and preliminary results [PDF]

, 2019
Background: GENetics of mOyaMoyA (GEN-O-MA) project is a multicenter observational study implemented in Italy aimed at creating a network of centers involved in moyamoya angiopathy (MA) care and research and at collecting a large series and bio ...
Acerbi, Francesco, Baracchini, Claudio, Bedini, Gloria, Bersano, Anna, Binelli, Simona, Blecharz, Kinga, Bono, Giorgio, Bruzzone, Maria Grazia, Calloni, Maria Vittoria, Capone, Fioravanti, Capra, Valeria, Caputi, Luigi, Caria, Filomena, Carolei, Antonio, Caso, Valeria, Cenzato, Marco, Ciceri, Elisa, Ciusani, Emilio, De Lodovici, Maria Luisa, Dell' Acqua, Maria Luisa, Di Lazzaro, Vincenzo, Di Piero, Vittorio, Esposito, Silvia, Faragò, Giuseppe, Farina, Filippo, Ferroli, Paolo, Franceschetti, Silvana, Fratianni, Alessia, Gioppo, Andrea, Grisoli, Marina, Lanfranconi, Silvia, Lasserve, Elisabeth Tournier, Marzoli, Stefania Bianchi, Nardocci, Nardo, Nava, Sara, null, null, Paciaroni, Maurizio, Pantaleoni, Chiara, Pantoni, Leonardo, Parati, Eugenio Agostino, Pavanello, Marco, Perrone, Patrizia, Pezzini, Alessandro, Prontera, Paolo, Raso, Alessandro, Riva, Daria, Romani, Alfredo, Sacco, Simona, Saletti, Veronica, Sanguigni, Sandro, Sarti, Cristina, Sebastiano, Davide Rossi, Toni, Danilo, Toscano, Massimiliano, Vajkoczy, Peter, Zedde, Maria Luisa, Zibordi, Federica, Zini, Andrea   +57 more
core   +1 more source

Endoscopy in achalasia [PDF]

Postgraduate Medical Journal, 1974
Summary In achalasia oesophagoscopy should be used to rule out definitely carcinoma of the cardia involving the myenteric plexus of the lower oesophageal sphincter. An easy passage of the instrument through the narrow terminal segment is characteristic but not always possible due to extreme distortion.
openaire   +3 more sources

“Pinstripe Pattern” in an Achalasia Patient

Clinical Medicine Insights: Gastroenterology, 2016
Endoscopic image of achalasia usually shows dilated esophageal cavity with retained liquids and foods. Recently, “pinstripe pattern” (PSP) in the case of achalasia patient was reported as an endoscopic image of the indicator for early detection of ...
Atsushi Imagawa, Keiko Takeuchi, Kozue Suto   +2 more
doaj   +1 more source

Contemporary esophageal physiological testing for primary esophageal motility disorder (PEMD) and gastroesophageal reflux disease (GERD) before bariatric surgery: A systematic literature review

Obesity Reviews, Volume 26, Issue 8, August 2025.
Summary Objective This systematic review was conducted to evaluate the preoperative prevalence of primary esophageal motility disorders and gastroesophageal reflux disease in patients with morbid obesity before bariatric surgery. Background The use of esophageal manometry ± 24‐hour pH study before bariatric surgery was explored.
Muhammed Ashraf Memon, Khorshed Alam, Zahirul Hoque, Shahjahan Khan   +3 more
wiley   +1 more source

Three Siblings With an Attenuated Presentation of Perlman Syndrome: A Case Report and Literature Review

Molecular Genetics &Genomic Medicine, Volume 13, Issue 7, July 2025.
We identified three siblings with novel biallelic variants in DISL32 and an attenuated Perlman syndrome phenotype. The proband presented with Wilms tumor and all three had fetal macrosomia, developmental delays, hypotonia, and dysmorphic facial features.
Alayne P. Meyer, Daniel C. Koboldt, Swetha Ramadesikan, Kristin Zajo, Maria E. Hernandez Gonzalez, Anthony R. Miller, Douglas Depoorter, Catherine P. Comer, James I. Geller, Katherine Somers, Nilay Shah, Marco L. Leung   +11 more
wiley   +1 more source

Botulinum Toxin as Preventive Treatment for Migraine: A Randomized Double-Blind Study [PDF]

, 2009
Aim: To determine if botulinum toxin type A (BoNT-A) injections can reduce the frequency and severity of migraines. Methods: Patients (n = 127) were randomized to receive placebo or two doses of BoNT-A (Dysport (R)). The primary endpoint was reduction in
Ceballos-Baumann, Andres, Petri, Susanne, Pfaffenrath, Volker, Stefenelli, Ulrich, Straube, Andreas, Toelle, Thomas   +5 more
core   +1 more source