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Achalasia: physiology and diagnosis

Annals of the New York Academy of Sciences, 2020
Achalasia is a rare motility disorder with incomplete relaxation of the lower esophageal sphincter and ineffective contractions of the esophageal body.
E. Rieder   +5 more
semanticscholar   +1 more source

Achalasia

Seminars in Pediatric Surgery, 2017
Achalasia is a rare neurogenic motility disorder of the esophagus, occurring in approximately 0.11 cases per 100,000 children. The combination of problems (aperistalsis, hypertensive lower esophageal sphincter (LES), and lack of receptive LES relaxation) results in patients having symptoms of progressive dysphagia, weight loss, and regurgitation ...
openaire   +3 more sources

Short‐term outcome after singular hydraulic EsoFLIP dilation in patients with achalasia: A feasibility study

Neurogastroenterology and Motility, 2020
Achalasia is a chronic esophageal motility disorder characterized by impaired relaxation of the lower esophageal sphincter, determined by an elevated integrated relaxation pressure (IRP > 15 mm Hg) and absent peristalsis.
Larissa Schnurre   +6 more
semanticscholar   +1 more source

Lower esophageal sphincter muscle of patients with achalasia exhibits profound mast cell degranulation

Neurogastroenterology and Motility, 2020
Eosinophils and mast cells are key effectors of allergy. When they accumulate in the esophagus, their myoactive, pro‐inflammatory, and cytotoxic products potentially could cause achalasia‐like motility abnormalities and neuronal degeneration.
Melissa R. Nelson   +15 more
semanticscholar   +1 more source

Hiccups and Achalasia

Annals of Internal Medicine, 1991
Excerpt Although esophageal disorders have been considered to cause hiccups (1, 2), the poor response of hiccups to anti-reflux surgery has led some investigators to question the role of reflux in ...
Howard Seeman, Morris Traube
openaire   +3 more sources

Coping with achalasia

Postgraduate Medicine, 1993
Achalasia is a primary esophageal motor disorder that is characterized by dysphagia, regurgitation, and chest pain. The diagnosis is suggested by narrowing with the classic "bird's beak" appearance of the distal esophagus. Esophageal manometry showing aperistalsis confirms the diagnosis. Pseudo-achalasia must be excluded with endoscopy.
openaire   +3 more sources

Treatment of achalasia

Current Treatment Options in Gastroenterology, 2005
Achalasia is a primary motility disorder of the esophagus that causes dysphagia. Normal esophageal motility and lower esophageal sphincter (LES) function can not be restored; thus treatment is directed at decreasing the pressure or disrupting the muscle fibers of the LES to allow passage of ingested material.
Jedediah A. Kaufman   +1 more
openaire   +3 more sources

Achalasia and pregnancy

BJOG: An International Journal of Obstetrics & Gynaecology, 1987
Summary. Forty‐one women with achalasia diagnosed between the ages of 18 and 45 years were interviewed and 37 of them who had been married at some time were asked to provide details of their fertility and reproductive histories. Thirty‐six agreed to do so and were compared with 36 healthy age‐matched women. The mean age at the time of study was 44 and
John F. Mayberry, M Atkinson
openaire   +3 more sources

Operation for Achalasia

2007
In 1913 Heller reported the first esophageal myotomy for achalasia through a left thoracotomy. Over the years, the transabdominal approach has been extensively adopted, especially in Europe. More recently, laparoscopy has emerged as the initial intervention of choice in several institutions throughout the world.
L. Bonavina, A. Peracchia
openaire   +2 more sources

SAGES guidelines for the use of peroral endoscopic myotomy (POEM) for the treatment of achalasia

Surgical Endoscopy, 2021
G. P. Kohn   +13 more
semanticscholar   +1 more source

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