Results 221 to 230 of about 8,048,933 (339)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Financial Achievability of the Florida Department of Transportation Research Projects : Putting the Financial Analysis Framework into Action

2018PDFTech ReportBDV30-977-12Financial analysisDecision makingTransportation planningTransportation system managementDecision-makingresearch processFloridaUnited StatesFlorida. Dept. of TransportationBorn, Patricia H.Dumm, Randy E.Eger, Robert J.Florida

core  

Exploring ISAC: Information-Theoretic Insights. [PDF]

Entropy (Basel)
Ahmadipour M, Wigger M, Shamai S.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Policy implementation and recommended actions to create healthy food environments using the Healthy Food Environment Policy Index (Food-EPI): a comparative analysis in South Asia. [PDF]

Lancet Reg Health Southeast Asia
Pineda E, Atanasova P, Wellappuli NT, Kusuma D, Herath H, Segal AB, Vandevijvere S, Anjana RM, Shamim AA, Afzal S, Akter F, Aziz F, Gupta A, Hanif AA, Hasan M, Jayatissa R, Jha S, Jha V, Katulanda P, Khawaja KI, Kumarendran B, Loomba M, Mahmood S, Mridha MK, Pradeepa R, Aarthi GR, Tyagi A, Kasturiratne A, Sassi F, Miraldo M.   +29 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Smartphone App Using Reinforcement Learning for Obesity: Single-Arm Feasibility Study. [PDF]

JMIR Hum Factors
Kurisu K, Yamamoto Y, Aoyama T, Yamauchi T, Yoshiuchi K.   +4 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Automated multivolume placental reconstruction using three-dimensional power Doppler ultrasound and infrared camera tracking. [PDF]

Ultrasound Obstet Gynecol
Xue A, Hanly R, Luichareonkit D, Thomas S, Barber T, Welsh AW.   +5 more
europepmc   +1 more source