Results 81 to 90 of about 8,048,933 (339)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ACHIEVEMENTS AND ASPIRATIONS [PDF]
n ...
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The rapid development of adaptation as a mainstream strategy for managing the risks of climate change has led to the emergence of a broad range of adaptation policies and management strategies globally. However, the success of such policies or management
C. Cvitanovic +4 more
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Achieving health or achieving wellbeing? [PDF]
AbstractThis article argues that achieving health and achieving wellbeing are different. The use of phenomenological and narrative approaches helped to elicit the meanings, nature and dimensions of wellbeing for ‘lay’ people, and also how wellbeing was maintained, lost and recovered. It indicates that the term ‘wellbeing’ has a much wider meaning than ‘
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Transition towards a circular bio economy potential feasibility and achievability
The Transition towards a Circular Bioeconomy potential feasibility and achievability, is a game between drivers of the transition and challenges of it. The study explores the relationships and links of those, and gradually uncovers which are the threats ...
Flick, Zacherie
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A statistics-based model for prediction of achievability of the planning criteria for IMRT planning
The purpose of this study is to develop and evaluate a statistics-based model to predict the achievability of the planning criteria for intensity-modulated radiation therapy planning.
Leung, HTL, Wong, KHW, Kwong, LWD
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