Results 151 to 160 of about 1,085,498 (298)

From belief to behavior: behavioral engagement as the proximal link between self-efficacy and L2 achievement. [PDF]

Front Psychol
Zhang G, Zhang FA, Li Y, Gong Y, He F.
europepmc   +1 more source

School achievement of children by demographic and socioeconomic factors, United States [PDF]

This is the second report on the school achievement of children 6-11 years of age in the noninstitutionalized population of the United States as estimated from the Reading and Arithmetic subtest data of the Wide Range Achievement Test (WRAT) obtained in ...

core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Mathematics Partial Associations with Subject-Specific Science Confidence: Evidence from 11 Education Systems in TIMSS 2023. [PDF]

Behav Sci (Basel)
Sideridis GD, Alghamdi M.
europepmc   +1 more source

Impact of the prior school environment on academic achievement of students at the secondary stage in Punjab (Pakistan) [PDF]

This study investigates the impact of the prior school environment on academic achievement of students at the secondary stage in Punjab (Pakistan). School environment is a very important school resource input.
Dahar, Rashida Ahmad, Dahar, Riffat Tahira, Dahar, Muhammad Arshad   +2 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Academic self-concept and ecological predictors of longitudinal change in reading achievement in Chile: evidence from a national study. [PDF]

Front Psychol
Salvo-Garrido S, Moraga-Pumarino A, Mieres-Chacaltana M, Polanco-Levicán K, Misciagno SA.   +4 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The association between school climate and mathematics achievement among middle school students: the serial indirect roles of mathematical bullying and psychological resilience and the moderating roles of grade level and gender. [PDF]

Front Psychol
Demir B, Beyazhancer R.
europepmc   +1 more source