Results 201 to 210 of about 771,630 (262)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

When avoiding failure helps: the interplay of achievement motivations, growth mindset, and career decision-making self-efficacy among pre-service teachers. [PDF]

Front Psychol
Liu M, Li RY, Huang YZ.
europepmc   +1 more source

Impact of academic stress on achievement among medical postgraduates: the moderating role of the Big Five personality traits. [PDF]

BMC Psychol
Li H, Gao R, Xu H.
europepmc   +1 more source

Perceived peer support and academic achievement among university students: the chain mediating roles of emotion regulation and behavioral engagement. [PDF]

Sci Rep
Gai G, Zhu X, Ahmad NS.
europepmc   +1 more source

Cumulative access to print books improves literacy achievement: Evidence from a five-year randomized trial in high-poverty schools. [PDF]

Proc Natl Acad Sci U S A
Borman GD, Yang H.
europepmc   +1 more source

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To achieve, or not to achieve complete revascularization

Catheterization and Cardiovascular Interventions, 2016
Key Points Prior to minimally invasive valve surgery, a strategy of complete revascularization did not impact overall survival. Angiographically guided revascularization may have resulted in unnecessary procedures. A larger sample size and greater atherosclerotic burden may be needed to observe an impact with complete revascularization.
Jorge A, Belardi, Mariano, Albertal
openaire   +2 more sources

Achievement in Microarchitecture

Communications of the ACM, 2023
David Papworth, a 30-year veteran of Intel, on what led to the P6 microprocessor and how that changed the microarchitectural paradigm.
openaire   +1 more source