Results 251 to 260 of about 2,768,933 (346)

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

Molecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker, Elysia Sarsam, Stuart J. Conway, Ester M. Hammond   +3 more
wiley   +1 more source

Quality and outcomes framework achievement and unplanned admissions for cardiovascular disease. [PDF]

BMC Health Serv Res
Hou B, Reece S, Moss RH, Hussain J, Lawton T, McCooe M, Sohal K, Abbas S, Doran T, Sheldon T, Dickerson J.   +10 more
europepmc   +1 more source

Canadian Federation, its Origins and Achievement; a Study in Nation Building

, 1926
E. M. Violette, Reginald G. Trotter
openalex   +2 more sources

The Achievement of Duchenne [PDF]

Proceedings of the Royal Society of Medicine, 1973
openaire   +3 more sources

Achievement of Bangladeshi heritage pupils [PDF]

, 2004

core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Culture, goal orientation and achievement of vocational college students. [PDF]

Front Psychol
Lin X, Lei P, Tan Q, Xiong B.
europepmc   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Screen Time and Standardized Academic Achievement Tests in Elementary School.

JAMA Netw Open
Li X, Keown-Stoneman CD, Omand JA, Cost KT, Gallagher-Mackay K, Hove J, Janus M, Korczak DJ, Pullenayegum EM, Tsujimoto KC, Vanderloo LM, Maguire JL, Birken CS, TARGet Kids! Collaboration.   +13 more
europepmc   +1 more source

Patient and surgeon predictors of achieving the critical view of safety in laparoscopic cholecystectomy: a prospective cohort study. [PDF]

Front Surg
Addasi R, Al-Sabe' L, AlRawabdeh K, Abu-Zayed R, Alaarag A, Ribeiro MAF, Helmy AH, El Muhtaseb MS, Daradkeh S.   +8 more
europepmc   +1 more source