Results 61 to 70 of about 193,068 (309)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Tes Esai Pemetaan Konsep sebagai Alat Ukur dalam Belajar Bermakna

open access: yesJurnal Ilmu Pendidikan, 2016
This study is a comparative study of an evaluation system between concept mapping essay test and multiple choice test on students' achievement in science. The study was carried out at primary schools in Cianjur.
Ida T. Sinambela
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

structural equation modeling on Test Anxiety and Locus of Control on Academic Achievement by Achievement Motivation as a mediator

open access: yesمجله علوم روانشناختی, 2018
Background:  Academic progress is one of the main priorities of schools, which is the main goal of education. Aims:  This study investigated Achievement Motivation as a mediator of the relationship between Test Anxiety and Locus of Control with Academic ...
Fatemeh Rasouli Khorshidi   +3 more
doaj  

EFEKTIVITAS PEMBELAJARAN MATEMATIKA DENGAN HYPNOTEACHING TERHADAP PRESTASI MAHASISWA PADA MATA KULIAH GEOMETRI II IKIP PGRI BOJONEGORO

open access: yesJurnal E-DuMath, 2017
The purpose of this research was to determine the effectiveness of mathematics learning by hypnoteaching on student achievement in the subject of geometry II. This research used quantitative approach and including a quasi-experimental research because it
Dian Nurul Safitri   +1 more
doaj   +1 more source

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