Ciprofloxacin enhances the stimulation of matrix metalloproteinase 3 expression by interleukin-1beta in human tendon-derived cells [PDF]
To determine whether the fluoroquinolone antibiotic ciprofloxacin, which can cause tendon pain and rupture in a proportion of treated patients, affects the expression of matrix metalloproteinases (MMPs) in human tendon-derived cells in culture.
Astrom +16 more
core +1 more source
Cast versus functional brace in the rehabilitation of patients treated non-operatively for a rupture of the Achilles tendon : protocol for UK Study of Tendo Achilles Rehabilitation (UK STAR) [PDF]
Introduction Achilles tendon rupture affects over 11,000 people yearly in the UK, and the incidence is increasing. Controversy remains with regards the best rehabilitation strategy for these patients.
Achten, J +9 more
core +6 more sources
The management of distal Achilles tendon rupture is still controversial, especially in elderly patients, due to poor bone quality and tendon stump integrity. One of the proposed repair techniques is by using an anchoring screw.
Teddy Heri Wardhana, Mukhlis Aziz
doaj +1 more source
Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells [PDF]
Fluoroquinolone antibiotics may cause tendon pain and rupture. We reported previously that the fluoroquinolone ciprofloxacin potentiated interleukin (IL)-1ß-stimulated expression of matrix metalloproteinases (MMP)-3 and MMP-1 in human tendon-derived ...
Corps, A.N +4 more
core +1 more source
Category: Sports Introduction/Purpose: Study Design: Case-control Objective: To determine whether patients presenting with an Achilles tendon rupture are at greater risk of rupturing their contralateral tendon when compared to general population. Summary
Joaquin Palma MD +6 more
doaj +1 more source
Bilateral Spontaneous Rupture of the Achilles Tendon as an Initial Presentation of Alkaptonuria: A Case Report [PDF]
Rupture of the Achilles tendon is a common occurrence in the athletic population with a history of injury; however, a complete rupture of both Achilles tendons is uncommon. Spontaneous rupture of the bilateral Achilles tendons is an even rarer phenomenon,
Sundara Raja Perumal, K Malathy, Anand
doaj +1 more source
Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies [PDF]
Versican is the principal large proteoglycan expressed in mid-tendon, but its role in tendon pathology is unknown. Our objective was to define the expression of versican isoform splice variant messenger ribonucleic acid (mRNA) in normal Achilles tendons,
Corps, AN +6 more
core +2 more sources
Staging achilles tendinopathy using ultrasound imaging: The development and investigation of a new ultrasound imaging criteria based on the continuum model of tendon pathology [PDF]
AimTo develop a standardised ultrasound imaging (USI)-based criteria for the diagnosis of tendinopathy that aligns with the continuum model of tendon pathology.
Ellis, Richard +4 more
core +1 more source
The STAMP Test: A Novel Clinical Test in Diagnosing Achilles Tendon Ruptures
Category: Ankle Introduction/Purpose: Achilles tendon ruptures are common injuries, and an estimated 20-25% injuries are missed acutely. Chronic and acute Achilles tendon rupture patients typically present with nonspecific complaints and physical exam ...
Giselle M. Porter +3 more
doaj +1 more source
Current treatment concepts for Achilles tendon rupture
Achilles tendon rupture is a common and primary cause of lower limb tendon injury suffered during sports-related activities. The causes of Achilles tendon rupture include the calf muscle and tendon overuse, poor tendon quality, and various medical ...
Chen-Chie Wang +4 more
doaj +1 more source

