Results 81 to 90 of about 11,039 (220)
Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami +2 more
wiley +1 more source
American Journal of Roentgenology, 1967 L O, Langer, P A, Baumann, R J, Gorlin
openaire +3 more sources
Obstructive sleep apnea in Norwegian adults with achondroplasia: a population-based study
Orphanet Journal of Rare Diseases, 2021 Background Previous studies have found a high prevalence of obstructive sleep apnea (OSA) in children with achondroplasia, but clinical studies on this complication in adults with achondroplasia are lacking.
Svein O. Fredwall +7 more
doaj +1 more source
C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia.
New England Journal of Medicine, 2019 BACKGROUND Achondroplasia is a genetic disorder that inhibits endochondral ossification, resulting in disproportionate short stature and clinically significant medical complications.
R. Savarirayan +18 more
semanticscholar +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Catalytic receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S259-S306, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Epidemiology and clinical management of nail clipping in dogs under UK primary veterinary care
Journal of Small Animal Practice, Volume 66, Issue 12, Page 925-933, December 2025.Objectives This study aimed to report the frequency, risk factors and clinical management of nail clipping in dogs under primary veterinary care across the United Kingdom during 2019 within the VetCompass Programme. Materials and Methods From a population of 2,250,741 dogs under veterinary care, 2440 nail clipping cases (3380 events) were randomly ...
L. A. Ahmed +4 more
wiley +1 more source
The Genomics Revolution in Nonmodel Species: Predictions vs. Reality for Salmonids
Molecular Ecology, Volume 34, Issue 23, December 2025.ABSTRACT The increasing feasibility of whole‐genome sequencing has been highly anticipated, promising to transform our understanding of the biology of nonmodel species. Notably, dramatic cost reductions beginning around 2007 with the advent of high‐throughput sequencing inspired publications heralding the ‘genomics revolution’, with predictions about ...
Samuel A. May +6 more
wiley +1 more source
Achondroplasia with SRY-positive 46, XX disorder of sex development: an extremely rare association
Endocrinology, Diabetes & Metabolism Case Reports, 2018 A 40-year-old man with achondroplasia presented with symptoms of hypogonadism, low libido and gynaecomastia. He was found to have hypergonadotropic hypogonadism, and karyotype and fluorescent in situ hybridisation analysis showed SRY-positive 46, XX ...
Yang Timothy Du, Angus Rutter, Jui Ho
doaj +1 more source
Perspectives on the Current and Future State of Artificial Intelligence in Medical Genetics
American Journal of Medical Genetics Part A, Volume 197, Issue 10, October 2025.ABSTRACT Artificial intelligence (AI) is rapidly transforming numerous aspects of daily life, including clinical practice and biomedical research. In light of this rapid transformation, and in the context of medical genetics, we assembled a group of leaders in the field to respond to the question about how AI is affecting, and especially how AI will ...
Benjamin D. Solomon +20 more
wiley +1 more source