Congenital CMV Infection: Determination of Transplacental Passage of Aciclovir by Ex Vivo Placental Perfusion. [PDF]
BJOGABSTRACT Objective To quantify the transplacental transfer of aciclovir at an amount equivalent to 2 g of valaciclovir corresponding to the fractionated dosing regimen given four times daily used to reduce congenital cytomegalovirus (CMV) transmission and to treat the CMV‐infected fetus. Design Experimental ex vivo study.
Ollivier H +9 more
europepmc +2 more sources
Impact of the BioFire FilmArray Meningitis-Encephalitis Panel on Management of Suspected Paediatric Central Nervous System Infections: A Single-Centre Retrospective Cohort Study. [PDF]
J Paediatr Child HealthABSTRACT Background Meningoencephalitis causes significant morbidity and mortality in children worldwide. Prompt diagnosis remains challenging, yet advances in molecular diagnostic technology have improved diagnostic performance. This study examined whether the introduction of the BioFire FilmArray meningitis/encephalitis (ME) multiplex panel impacted ...
Churcher LM +4 more
europepmc +2 more sources
Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators. [PDF]
FEBS JAutophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Fichtner J +13 more
europepmc +2 more sources
Paroxysmal Nocturnal Haemoglobinuria-Associated Acute Cutaneous Thrombosis and Haemolysis in the Setting of Parvovirus B19 and Varicella Zoster Virus Infection. [PDF]
EJHaemABSTRACT A 28‐year‐old male with paroxysmal nocturnal haemoglobinuria (PNH) presented with headache, nasal bridge discomfort and haemoglobinuria. He developed a macular‐papular rash which rapidly progressed into purpura, necrosis and peri‐orbital oedema. Investigations demonstrated severe haemolytic anaemia and acute parvovirus B19 infection.
Potter LJ +9 more
europepmc +2 more sources
Aciclovir‐resistenter Zoster disseminatus bei chronischer lymphatischer B‐Zell‐Leukämie [PDF]
J Dtsch Dermatol GesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 1, Page 87-90, January 2026.
Turan T +3 more
europepmc +2 more sources
Aciclovir no tratamento da varicela em idade pediátrica: Revisão baseada na evidência
Revista Portuguesa de Medicina Geral e Familiar, 2009 Objectivos: A varicela é uma doença benigna que afecta sobretudo as crianças, sendo a taxa de incidência em Portugal (2005) de 2,37%.Apesar de auto-limitada, é altamente contagiosa e podem ocorrer complicações em 5-10% de todos os indivíduos afectados.
Tânia Colaço +2 more
doaj +1 more source
Hydroa Vacciniforme Lymphoproliferative Disorder With a Truncating KLF2 Variant Presenting as Benign Photodermatoses. [PDF]
Photodermatol Photoimmunol PhotomedPhotodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 3, May 2026.
Warner-Levy J +3 more
europepmc +2 more sources
Encefalopatía como forma de presentación de la COVID-19
Revista Cubana de Medicina Militar, 2021 Introducción: El virus SARS-CoV-2, responsable de la COVID-19 presenta una alta tasa de contagio y es capaz de producir afecciones a diferentes niveles en el organismo, e incluye el sistema nervioso central, con manifestaciones como crisis convulsiva ...
Jorge Félix Nuñez Martínez +4 more
doaj
Anais da Academia Brasileira de Ciências, 2015 We performed a systematic review with the objective of verifying the efficacy of topical use 5% Acyclovir-1% Hydrocortisone cream compared to the placebo group for herpes simplex labialis treatment. We performed a literature search using MEDLINE, Embase,
MARIA INÊS DA ROSA +5 more
doaj +1 more source
Revista Brasileira de Reumatologia, 2007 Infecção pelo vírus varicela zoster (VVZ) em pacientes com lúpus eritematoso sistêmico juvenil (LESJ) tem sido pouco descrita. Durante um período de 12 anos, ocorreram 195 internações em 77 pacientes com LESJ e estas foram acompanhadas pela Unidade de ...
Paula da Silva Neves +5 more
doaj +1 more source