Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Solvent Deuterium Isotope Effects on Acid-Base Reactions. Part II. Variation of the First and Second Acidity Constants of Carbonic and Sulfurous Acids in Mixtures of Light and Heavy Water. [PDF]
, 1969 Pentti Salomaa +7 more
openalex +1 more source
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Biodiesel Production from Spent Fish Frying Oil Through Acid-Base Catalyzed Transesterification [PDF]
Pakistan Journal of Analytical & Environmental Chemistry, 2012 Biodiesel fuels were prepared from a special type of frying oil namely spent fish frying oil through two step transesterification viz. acid-base catalyzed transesterification.
Abdalrahman B. Fadhil +3 more
doaj
Solvent Deuterium Isotope Effects on Acid-Base Reactions. Part IV. Lyonium Ion-Catalyzed Hydrolysis of Tertiary Butyl Acetate in Isotopically Different Waters. [PDF]
, 1969 Pentti Salomaa +7 more
openalex +1 more source
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
Improving heterogeneous catalysis for biodiesel production process
Cleaner Chemical Engineering, 2022 The relevance of heterogeneous catalysis in biodiesel production cannot be overemphasized, as heterogeneous catalysts have eliminated the demerits associated with a homogeneous catalysts.
Onukwuli Dominic Okechukwu +3 more
doaj
Nitrometbane as Polar Solvent : Part II. Acid-Base Neutralisation Reactions in Nitromethane [PDF]
, 1969 Ram Chand Paul +2 more
openalex +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source