Results 121 to 130 of about 4,964,055 (321)

Reaction mechanism of hydrogen activation by frustrated Lewis pairs

Green Energy & Environment, 2019
Typically, a Lewis acid and a Lewis base can react with each other and form a classical Lewis adduct. The neutralization reaction can however be prevented by ligating the acid and base with bulky substituents and the resulting complex is known as a ...
Lei Liu, Binit Lukose, Pablo Jaque, Bernd Ensing   +3 more
doaj  

Structural and Surface Characterization of Newly Synthesized D-π-D Type Schiff Base Ligand: (1E,2E)-3-[4-(Dimethylamino)phenyl]prop-2-en-1-ylidene)phenylamine

Journal of Chemistry, 2013
A new Schiff base with D-π-D type, (1E,2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene)phenylamine, has been successfully synthesized using the reaction of (2E)-3-[4-(dimethylamino)phenyl]acrylaldehyde with aniline.
Gulsah Gumrukcu, Serkis Garikyan, Gulnur Keser Karaoglan, Dolunay Sakar   +3 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Mechanisms of the Bridge Cleavage Reactions of Di-µ-hydroxo-, µ-Hydroxo-µ-oxo-, and Di-µ-oxo-bis { bis( o-phenanthroline )chromium(III)} Complex Ions in Acid and Base Media [PDF]

, 1998
SHAMBHUNATH BISAI, ASHOKE KUMAR SINGH, BISWANATH CHAKRAVARTY   +2 more
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Acid–base properties and active site requirements for elimination reactions on alkali-promoted MgO catalysts [PDF]

, 2000
V.K. Dı́ez
openalex   +1 more source

The roles and applications of extracellular vesicles in cancer

Molecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Reaction mechanism of quasi-free knockout processes in exotic RI beam era [PDF]

arXiv
The quasi-free nucleon knockout reaction has been revealed the single-particle nature of nuclei. Thanks to the advances in experimental techniques and reaction theory, various new aspects of nuclei are being revealed by knockout reactions. In this article, we review the basic concept of the quasi-free knockout reaction, and recent achievements in the ...
arxiv