TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
A new synthesis of enantiomerically pure syn-(S)-β-hydroxy-α-amino acids via asymmetric aldol reactions of aldehydes with a homochiral Ni(II)-glycine/(S)-BPB Schiff base complex [PDF]
Yuri N. Belokoń+5 more
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
PROFIL MODEL MENTAL SISWA PADA POKOK BAHASAN TITRASI ASAM LEMAH OLEH BASA KUAT BERDASARKAN TDM-IAE [PDF]
Penelitian ini berjudul “PROFIL MODEL MENTAL SISWA PADA POKOK BAHASAN TITRASI ASAM LEMAH OLEH BASA KUAT BERDASARKAN TDM-IAE”. Penelitian ini dilakukan di salah satu SMA Negeri di Kota Bandung dengan enam orang siswa kelas XII IPA sebagai subjek ...
Utami, Riska Padmi Dwi
core
Reaction between N-Alkylhydroxylamines and Chiral Enoate Esters: More Experimental Evidence for a Cycloaddition-like Process, a Rationale Based on DFT Theoretical Calculations, and Stereoselective Synthesis of New Enantiopure β-Amino Acids [PDF]
Albertina G. Moglioni+6 more
openalex +1 more source
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source
A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays [PDF]
Sharon Chen+2 more
openalex +1 more source
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef+10 more
wiley +1 more source
Acid-base reactions and kinetics of the halates in fused nitrates
James M. Schlegel
openalex +1 more source
Lewis Base Activation of Lewis Acids. Vinylogous Aldol Reactions. [PDF]
Scott E. Denmark, Gregory L. Beutner
openalex +1 more source