Matrix: a complex amalgam of structures and functions in tumor microenvironment
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis+3 more
wiley +1 more source
Preparation and Physicochemical Properties of a New Biolubricant from Epoxidized Fatty Acids and Diethylene Glycol Monomethyl Ether. [PDF]
Chaiendoo K+2 more
europepmc +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang+6 more
wiley +1 more source
Efficient formation of C<sub>3</sub> and C<sub>4</sub> hydrocarbons from cellulose over Pt/Mg-doped ZrO<sub>2</sub> catalysts without hydrogen addition. [PDF]
Ofuchi Y+8 more
europepmc +1 more source
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda+9 more
wiley +1 more source
Aqueous-Phase Multicomponent Reaction Mechanism for the Synthesis of Pyrido[2,3‑<i>d</i>]pyrimidines: A Theoretical Perspective. [PDF]
Rufino VC, Amarante GW, Dos Santos HF.
europepmc +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić+3 more
wiley +1 more source
Role of Individual Amino Acid Residues Directly Involved in Damage Recognition in Active Demethylation by ABH2 Dioxygenase. [PDF]
Davletgildeeva AT+5 more
europepmc +1 more source