ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang+11 more
wiley +1 more source
Supramolecular assembly properties of a mixed-sequence recognition-encoded melamine oligomer.
Dhiman M, Smith JT, Hunter CA.
europepmc +1 more source
Mechanistic insights into base-free nickel-catalyzed Suzuki-Miyaura cross-coupling of acid fluoride and the origin of chemoselectivity: a DFT study. [PDF]
Dagnaw WM, Hailu YM, Mohammed AM.
europepmc +1 more source
An Electrolytic System Based on the Acid-Base Reaction between Solid-Supported Acids and Water
Yumiko Miura, Hiroyuki Tateno, T. Tajima
openalex +2 more sources
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó+17 more
wiley +1 more source
Design of mismatch closure for enhanced specificity in DNA strand displacement reactions. [PDF]
Yu H+15 more
europepmc +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer+11 more
wiley +1 more source
Process Integration and Life-Cycle Assessment of Moist-Solid Hydrolysis of Polylactic Acid with Lactic Acid Recovery via Electrodialysis. [PDF]
Luo H+6 more
europepmc +1 more source
Ultrasonic and Densimetric Titration Applied for Acid-base Reactions
Andrzej Burakowski, Jacek Gliński
openalex +1 more source
Objective The Plants for Joints (PFJ) intervention, including a whole‐food plant‐based diet, exercise, and stress reduction, reduced signs and symptoms of rheumatoid arthritis (RA) or metabolic syndrome–associated hip or knee osteoarthritis (MSOA) compared to usual care.
Carlijn A. Wagenaar+10 more
wiley +1 more source