Results 251 to 260 of about 1,113,567 (292)

Glaser Heterocoupling Reaction for the Synthesis of Enantiomerically Enriched Unnatural α‑Amino Acids Incorporating Asymmetric Diyne Moieties: Mechanistic Insights and Optimization. [PDF]

ACS Omega
Hayriyan L, Tovmasyan A, Grigoryan A, Ghazaryan K, Biondi B, Dallakyan OL, Chobanyan MS, Zakaryan H, Saghyan A, Mkrtchyan A.   +9 more
europepmc   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Enhancement of biological properties in casein protein through functionalization with cinnamaldehyde <i>via</i> Schiff base bonding: antibacterial and antioxidant effects. [PDF]

RSC Adv
Hendy A, Hassan N, El-Nady J, Ahmed ASI, Abou Shahba RM, Tamer TM.   +5 more
europepmc   +1 more source

Correction: Acid-catalyzed carboxylic acid esterification and ester hydrolysis mechanism: acylium ion as a sharing active intermediate via a spontaneous trimolecular reaction based on density functional theory calculation and supported by electrospray ionization-mass spectrometry

, 2015
Hongchang Shi, Yilei Wang, Ruimao Hua
openalex   +2 more sources

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Catalyst-Driven Improvements in Conventional Methods for Imine-Linked Covalent Organic Frameworks. [PDF]

Molecules
Jafari M, Peng Z, Samie A, Taghavi F, Khojastehnezhad A, Siaj M.   +5 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Amplification-Free Detection of Circulating microRNA Biomarkers from Body Fluids Based on Fluorogenic Oligonucleotide-Templated Reaction between Engineered Peptide Nucleic Acid Probes: Application to Prostate Cancer Diagnosis

, 2016
Gavin A D Metcalf, Akifumi Shibakawa, Hinesh Patel, Ailsa Sita-Lumsden, Andrea Zivi, Nona Rama, Charlotte L. Bevan, Sylvain Ladame   +7 more
openalex   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Direct sequencing of DNA 5-methylcytosine by engineered dioxygenase NTET-assisted eNAPS. [PDF]

Chem Sci
Zhang S, Xie NB, Zeng L, Gang FY, Gu YH, Wang M, Guo X, Ji TT, Xiong J, Yuan BF.   +9 more
europepmc   +1 more source