Results 51 to 60 of about 1,113,567 (292)

Synthesis and Characterization of Some New Benzimidazole Derivatives

open access: yesمجلة بغداد للعلوم, 2016
In this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using ...
Baghdad Science Journal
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Synthesis of peptides employing Fmoc-amino acid chlorides and commercial zinc dust [PDF]

open access: yes, 1998
Coupling of Fmoc-amino acid chlorides mediated by activated commercial zinc dust for the synthesis of peptides is described. The reaction is carried out in an organic medium.
Gopi, H.N., Sureshbabu, V.V.
core   +1 more source

A Lewis Acid-Promoted Michael Addition and Ring-Expansion Cascade for the Construction of Nitrogen-Containing Medium-Sized Rings

open access: yesMolecules, 2023
A Lewis acid-promoted annulation of azadienes and cyclobutamines was developed. This reaction proceeded through Michael addition and ring-expansion cascade, affording the corresponding nitrogen-containing medium-sized rings with a broad scope in moderate
Jiaming Wang, Jia Li, Changgui Zhao
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Synthesis and optimization ring opening of monoepoxide linoleic acid using p-toluenesulfonic acid [PDF]

open access: yes, 2013
Biolubricant base oils, 9,12-hydroxy-10,13-oleioxy-12-octadecanoic acid (HYOOA) was synthesized based on the esterification reaction of Monoepoxide linoleic acid 9(12)-10(13)-monoepoxy 12(9)-octadecanoic acid (MEOA) with oleic acid (OA) and catalyzed by ...
Bashar Abdullah   +4 more
core   +1 more source

Acid and Base Catalyzed Transesterification of Animal Fats to Biodiesel [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2008
The present study has been focused on the acid and base transesterification of animal fats (dairy cow and beef) to produce biodiesel by varying process parameters such as catalyst amount, catalyst nature, reaction time and temperature.
Haq Bhatti   +3 more
doaj  

Study on the Corrosion Kinetics of Iron in Acid and Base Medium

open access: yesE-Journal of Chemistry, 2011
The kinetics of corrosion of iron in acid and base medium by weight loss method was investigated. The corrosion kinetics was studied in sulphuric acid, nitric acid and potassium hydroxide by weight loss method at different time intervals at 25.0 °C to 40.
D. B. Patil, A. R. Sharma
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Mixing characterization inside microdroplets engineered on a microcoalescer [PDF]

open access: yes, 2007
We use a microdevice where microdroplets of reagents are generated and coalesce in a carrier continuous phase. The work focuses on the characterization of the mixing step inside the droplets, in the perspective to use them for chemical kinetic data ...
Cristobal, Galder   +5 more
core   +1 more source

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