Results 111 to 120 of about 6,551,457 (314)

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent WO 2007/042510 A2) [PDF]

open access: yes, 2007
The present invention relates to a new process for the production of arachidonic acid and/or eicosapentaenoic acid in plants through the co-expression of a ?-12-/?-15- desaturase, ?-9-elongase, ?-8-desaturase and a ?-5-desaturase and a process for the ...
Sayanova, O. V., Napier, J. A.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Conformations of 2-phenyl-3-pyridylpropenoic acid (alpha-phenyl pyridylcinnamic acid) dimers – A computational study

open access: yes, 2005
Motivation. Cinnamic acid analogs are not only important parts of the shikimic acid metabolic pathway of higher plants but it is possible to assemble, particularly from those containing oxygen or nitrogen heteroatoms, various patterned structures kept ...
Pálinkó István, Pálinkó, István
core  

The Effect of Combined Sandblasting and Piranha Solution Treatment on Resin Cement Bond Strength to Zirconia: An In Vitro Study

open access: yesCeramics
This in vitro study investigated whether piranha solution treatment, applied alone or following sandblasting, enhances the shear bond strength of resin cement to zirconia. Fifty zirconia specimens were assigned to five groups: no treatment, sandblasting (
Apichai Maneenacarith   +5 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 8273958 B2) [PDF]

open access: yes, 2012
The present invention relates to a new process for the production of arachidonic acid and/or eicosapentaenoic acid in plants through the co-expression of a Δ-12-/Δ-15-desaturase, Δ-9-elongase, Δ-8-desaturase and a Δ-5-desaturase and a process for the ...
Sayanova, O. V., Napier, J. A.
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Process For The Production Of Arachidonic Acid And/or Eicosapentaenoic Acid (Patent US 8258371 B2) [PDF]

open access: yes, 2012
The present invention relates to a new process for the production of arachidonic acid and/or eicosapentaenoic acid in plants through the co-expression of a Δ-12-/Δ-15-desaturase, Δ-9-elongase, Δ-8-desaturase and a Δ-5-desaturase and a process for the ...
Sayanova, O. V., Napier, J. A.
core  

Antitumor activity of genetically engineered NK-cells in non-hematological solid tumor: a comprehensive review

open access: yesFrontiers in Immunology
Recent advancements in genetic engineering have made it possible to modify Natural Killer (NK) cells to enhance their ability to fight against various cancers, including solid tumors.
Chinmayee Priyadarsini Dash   +9 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

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