Results 251 to 260 of about 90,125 (307)

A platinum butterfly effect: small changes turn an anticancer drug into a non-toxic metalloantibiotic with in vivo efficacy. [PDF]

NPJ Antimicrob Resist
Özsan Ç, Schäfer AB, Akhir A, Aning OA, Fulgencio S, Maitra R, Rani R, Saxena D, Westerlund F, Chopra S, Wenzel M, Frei A.   +11 more
europepmc   +1 more source

Butyrylcholinesterase-Loaded Liposomes and Polymersomes: Catalytic Parameters for Three Types of Substrates. [PDF]

Int J Mol Sci
Shaihutdinova Z, Batasheva S, Masson P, Pashirova T.   +3 more
europepmc   +1 more source

Urea cycle defects in adulthood: clinical presentation, diagnosis and treatment in genetically encoded hepatic metabolic disorders with a potential for encephalopathy. [PDF]

Metab Brain Dis
Das AM.
europepmc   +1 more source

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Cephalosporins are scavengers of hypochlorous acid

Biochemical Pharmacology, 1995
Potential scavenging properties of cephalosporins (i.e. cefamandole, cefotaxime and ceftriaxone) towards hypochlorous acid (HOCl) as well as the antibacterial activity of control and HOCl-reacted antibiotics were investigated. We found that these drugs, at therapeutically relevant concentrations, are indeed scavengers of HOCl, with ceftriaxone showing ...
LAPENNA, Domenico, CELLINI, Luigina, de Gioia S, MEZZETTI, Andrea, CIOFANI, Giuliano, FESTI, Davide, CUCCURULLO, Franco   +6 more
openaire   +3 more sources

Chlorogenic Acid as a Natural Scavenger for Hypochlorous Acid

Biochemical and Biophysical Research Communications, 1995
The effect of chlorogenic acid (CGA) on the killing of Escherichia coli by hypochlorous acid (HOCI) was examined. CGA prevented E. coli from bactericidal action of HOCI in a concentration-dependent manner. HOCI reacted rapidly with CGA. By comparison with the one- and two-electron oxidation products produced by peroxidase and phenolase reactions ...
Y, Kono, H, Shibata, Y, Kodama, A, Ueda, Y, Sawa   +4 more
openaire   +2 more sources

Ambroxol Is a Scavenger of Hypochlorous Acid and Monochloramine

Pharmacology, 1994
Experimental studies have suggested that ambroxol, a drug clinically used to enhance pulmonary surfactant production, may also exert some anti-inflammatory effects, though specific mechanisms are not yet fully understood. Thus, potential scavenging properties of ambroxol towards the most toxic neutrophil-arising prooxidants hypochlorous acid and ...
LAPENNA, Domenico, de Gioia S, CIOFANI, Giuliano, CUCCURULLO, Franco   +3 more
openaire   +3 more sources

Polycationic Nanofibers for Nucleic Acid Scavenging

Biomacromolecules, 2016
Dying cells release nucleic acids (NA) and NA-containing complexes that activate inflammatory pathways of immune cells. Sustained activation of these pathways contributes to chronic inflammation frequently encountered in autoimmune and inflammatory diseases.
Jennifer G, Jackman, Hemraj, Juwarker, Luke P, Poveromo, Howard, Levinson, Kam W, Leong, Bruce A, Sullenger   +5 more
openaire   +2 more sources

Hydroxybenzoic acids and their derivatives as peroxynitrite scavengers

Free Radical Biology and Medicine, 2014
A social challenge of the 21(st) century is to reduce the incidence of chronic diseases. A balanced diet rich in polyphenols could contribute to reduce the risk and to the prevention of diabetes, coronary heart disease, cancer, Alzheimer's diseases and cataract(1).
Beáta, Hubková, Beáta, Veliká, Anna, Birková, Juraj, Guzy, Mária, Mareková   +4 more
openaire   +2 more sources

Hypochlorous acid scavenging capacity of garlic

Phytotherapy Research, 2007
AbstractThe ability of the following aqueous garlic extracts to scavenge hypochlorous acid (HOCl) was studied: (a) unheated extract of raw garlic (RG), (b) heated extract of raw garlic (HRG), (c) extract of boiled garlic cloves (BG) and (d) extract of microwave‐treated garlic cloves (MG).
José, Pedraza-Chaverrí, Gabriela, Arriaga-Noblecía, Omar Noel, Medina-Campos   +2 more
openaire   +2 more sources