Results 201 to 210 of about 803,542 (263)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

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On the assay for glutathione in acid solution

Analytical Biochemistry, 1968
Abstract The assay recently described (1) for glutathione in an acid medium has been found to include the naturally occurring S -sulfoglutathione. It is pointed out that this method, in combination with ion-exehange chromatography, may actually make up a suitable determination of S -sulfoglutathione.
B, Eriksson, R, Tabova
openaire   +2 more sources

Conformation of polyribouridylic acid in solution

Journal of Molecular Biology, 1970
Abstract The conformation of polyribouridylic acid in aqueous solution has been studied under ideal solvent conditions, using light scattering, viscometry and sedimentation velocity and equilibrium measurements. The unperturbed dimensions of the poly rU molecule do not vary greatly with temperature, as expected for a polynucleotide with little or no ...
L D, Inners, G, Felsenfeld
openaire   +2 more sources

Fluorosilicate equilibria in acid solution

Polyhedron, 1988
Abstract The reaction between silicic acid and the fluoride ion in aqueous solution has been investigated at 25°C in a 3 m (Li)ClO 4 medium, by potentiometric methods employing a fluoride ion-selective electrode to observe the free hydrogen fluoride concentration.
CIAVATTA L, IULIANO, MAURO, PORTO R.
openaire   +3 more sources

Sonophotocatalysis of oxalic acid solution

Ultrasonics, 2006
Sonophotocatalysis of oxalic acid was performed in various atmospheric conditions. Sonophotocatalysis means a coupled reaction of sonolysis and photocatalysis. CO(2), CO and H(2) were obtained. The yield of CO(2) was twice larger than the sum of yields of photocatalysis and sonolysis in an Ar atmosphere. Namely, synergistic effect was observed. Further
Hisashi, Harada, Hisashi, Tanaka
openaire   +2 more sources