Results 91 to 100 of about 115,096 (255)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Chemical dynamics [PDF]

open access: yes, 1968
CHEMICAL EDUCATION is changing rapidly, not only because of the explosive growth of knowledge but also because the new knowledge has stimulated reformulation of working principles in the science.
Dence, Joseph B.   +2 more
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Stability of encapsulated and non-encapsulated anthocyanin in yogurt produced with natural dye obtained from Solanum melongena L. Bark

open access: yesRevista Brasileira de Fruticultura
This research evaluated the stability of non-encapsulated and spray-dried encapsulated anthocyanin from Solanum melongena L. bark as a natural dye in yogurts.
Flavia Jamille de Figueiredo Paes Barretto   +3 more
doaj   +1 more source

Content of metals and organic acids from experimental sparkling white wine

open access: yesBIO Web of Conferences, 2017
This work is focused on the study of the influence of different strains of yeasts on the concentration of organic acids, metallic content, and other physical-chemical parameters from experimental sparkling white wines produced by traditional method ...
Focea Mihai Cristian   +6 more
doaj   +1 more source

Preyssler Heteropolyacids in the Self-Etherification of 5-Hydroxymethylfurfural to 5,5′-[Oxybis(methylene)]bis-2-furfural Under Mild Reaction Conditions [PDF]

open access: yes, 2017
The synthesis of 5,5′-[oxybis(methylene)]bis-2-furfural (OBMF) from 5-hydroxymethylfurfural (5-HMF) was studied using bulk and alumina-supported Preyssler heteropolyacids (HPAs). The formation of OBMF was related to the amount of Brønsted acid sites, and
Afonso, Carlos A. M.   +6 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Sorption and activation of hydrocarbons by molecular sieves [PDF]

open access: yes, 1997
Substantial progress has been made recently in the understanding of sorption and activation of alkanes. This progress reflects the emergence of new theoretical and experimental results, leading to a more quantitative picture of the elementary steps ...
Lercher, Johannes A.   +1 more
core   +2 more sources

Dissociation Constants of Thiolactic Acid

open access: yesZeitschrift für Physikalische Chemie, 1971
The acid dissociation constants of thiolactic acid have been determined potentiometrically and polarographically at three diffrent temperatures, \(pK_{D_1}\)values· have been found to be 3·63, 3·66 and 3·70 and \(pK_{D_2}\) values as 10.24, 10·18 and 10·11 at 20°,30° and 40° respectively.
R. S. Saxena, Singh, Pratap
openaire   +2 more sources

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