Results 91 to 100 of about 3,274,216 (342)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Study of β-Cyclodextrin Effect on Acidity Constant of 2-(2H-Benzo(d)(1,2,3) triazol-2-yl) phenol by Spectrophotometry

E-Journal of Chemistry, 2010
The interaction of solutes with β-cyclodextrin leads to apparent changes in their chemical properties, such as shifts in their absorption spectra and acid-base equilibrium.
Amir H. M. Sarrafi, Elahe Konoz, Negin Ghorashi   +2 more
doaj   +1 more source

Novel B(Ar')2(Ar'') hetero-tri(aryl)boranes: a systematic study of Lewis acidity [PDF]

, 2016
A series of homo- and hetero-tri(aryl)boranes incorporating pentafluorophenyl, 3,5-bis(trifluoromethyl)phenyl, and pentachlorophenyl groups, four of which are novel species, have been studied as the acidic component of frustrated Lewis pairs for the ...
Ashley, Ashley, Bayne, Beckett, Binding, Blagg, Bourhis, Cairncross, Chase, Clark, Cummings, Dolomanov, Dureen, Elliot J. Lawrence, Elliot L. Bennett, Farrell, Fulmer, Georgina R. Hatton, Gregory G. Wildgoose, Gyömöre, Herrington, James M. Courtney, Konze, Lawrence, Lawrence, Lawrence, Lawrence, LeSuer, Lu, Mahdi, Mahdi, Mayer, McCahill, Ménard, Ménard, Nödling, Otten, Palatinus, Palatinus, Palatinus, Robin J. Blagg, Sajid, Samigullin, Schäfer, Scott, Scott, Scott, Sheldrick, Sheldrick, Sivaev, Stephan, Stephan, Stephan, Stephan, Stephan, Stephan, Travis, Trevor R. Simmons, Waerder, Wang, Welch, Zaher   +61 more
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Effects of acid rain on competitive releases of Cd, Cu, and Zn from two natural soils and two contaminated soils in hunan, China [PDF]

, 2007
Leaching experiments of rebuilt soil columns with two simulated acid rain solutions (pH 4.6– 3.8) were conducted for two natural soils and two artificial contaminated soils from Hunan, southcentralChina, to study effects of acid rain on competitive ...
Guo, Zhao-hui, Liao, Bo-han, Probst, Anne, Probst, Jean-Luc, Zeng, Qingru   +4 more
core   +3 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Evaluation of Acidity Constants and Evolution of Electronic Features of Phenol Derivatives in Different Compositions of Methanol/Water Mixture

Journal of Chemistry, 2013
This work was devoted to evaluation of acidity constants of 28 phenol derivatives in 11 different compositions of methanol/water solvent mixtures. The Onsager reaction field model was applied to any molecule of phenol derivatives dissolved in binary ...
Mahmood Sanchooli
doaj   +1 more source

The Proton Dissociation of Bio-Protic Ionic Liquids: [AAE]X Amino Acid Ionic Liquids

Molecules, 2020
[AAE]X composed of amino acid ester cations is a sort of typically “bio-based” protic ionic liquids (PILs). They possess potential Brønsted acidity due to the active hydrogens on their cations. The Brønsted acidity of [AAE]X PILs in green solvents (water
Ting He, Cheng-Bin Hong, Peng-Chong Jiao, Heng Xiang, Yan Zhang, Hua-Qiang Cai, Shuang-Long Wang, Guo-Hong Tao   +7 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Determining kinetic constants and transport efficiencies at membrane interfaces to optimize the removal/recovery of Cu(II) through lulk liquid membranes containing benzoylacetone as carrier [PDF]

, 2017
The removal, separation, and enrichment of heavy metals in aqueous solutions has become a prime concern over the last few decades because of both their adverse effects on the ecosystem and living organisms and their valuable resource character.
Gómez Gómez, Elisa, Hidalgo Montesinos, Asunción María, León Albert, Gerardo, Miguel Hernández, Beatriz, Murcia Almagro, María Dolores   +4 more
core   +2 more sources