Results 61 to 70 of about 771,384 (234)

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

A case report and literature review of primary distal renal tubular acidosis resulting from a mutation in ATP6V0A4

Frontiers in Pediatrics
Primary renal tubular acidosis is an inherited disorder with heterogeneous clinical presentations, including chronic metabolic acidosis, electrolyte imbalances (e.g., hypokalemia), skeletal abnormalities, and urinary tract symptoms.
Chenyang Chang, Hao Chen, Min Wang, Jingshan Chen, Yaomin Zou, Shaowen Hu, Shaowen Hu, Shaowen Hu, Kaiyuan Luo, Kaiyuan Luo, Kaiyuan Luo, Kaiyuan Luo, Xingyu Rao, Xingyu Rao, Xingyu Rao, Huifang Zhu, Huifang Zhu, Huifang Zhu, Huifang Zhu   +18 more
doaj   +1 more source

Everything you need to know about distal renal tubular acidosis in autoimmune disease [PDF]

, 2014
Renal acid-base homeostasis is a complex process, effectuated by bicarbonate reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular acidosis (RTA).
Ewout J. Hoorn, Both, T. (Tim), P. Martin van Hagen, Daele, P.L.A. (Paul) van, Hoorn, Ewout; id_orcid, Virgil A. S. H. Dalm, van Laar, Jan, Zietse, R., van Daele, Paul; id_orcid, Both, Tim, Hagen, P.M. (Martin) van, Paul L. A. van Daele, van Hagen, P.M., Dalm, V.A.S.H., Zietse, R. (Bob), Hoorn, E.J. (Ewout), Laar, J.A.M. (Jan) van, Robert Zietse, Jan A. M. van Laar, Dalm, V.A.S.H. (Virgil), Tim Both   +20 more
core   +1 more source

Multisystem developmental abnormalities and insulin resistance in ADTKD‐HNF1B with the p.E105K variant: A clinical conundrum

Diabetic Medicine, EarlyView.
Abstract Aims HNF1B variants cause autosomal dominant tubulointerstitial kidney disease (ADTKD‐HNF1B), but the phenotypic spectrum of variants of uncertain significance (VUS) remains incompletely defined. We aimed to characterise the multisystem phenotype associated with the HNF1B p.E105K variant and to examine the mechanism underlying insulin ...
YunZe Wang, KangChun Xu, PengFei Liu, Bin Wang, Yan Yang, ShanZhai Wei   +5 more
wiley   +1 more source

GLP‐1–Based Therapy in Type 1 Diabetes: Balancing Efficacy, Safety, and Patient Selection

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To critically examine the evolving evidence on glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and the dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonist tirzepatide as adjuncts to insulin therapy in type 1 diabetes (T1D), with particular emphasis on their benefit–risk balance in individuals with ...
Thales Rossatto, Ricardo de Andrade Oliveira, Andréia Machado Cardoso   +2 more
wiley   +1 more source

Acidose tubular renal tipo I: relato de um caso. [PDF]

, 1983
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Pereira, Leila Denise Cesário
core  

Anaesthetic management of a horse with acute kidney injury

Equine Veterinary Education, EarlyView.
Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source

Primary Sjögren's Syndrome First Presenting as Hypokalemic Quadriparesis

The Turkish Journal of Gastroenterology, 2017
Hypokalemic paralysis and respiratory failure associated with distal renal tubular acidosis as first clinical manifestation of primary Sjögren's syndrome has been reported a few times.
Rolando MARTÍNEZ-GRANADOS, Guillermo DELGADO-GARCÍA, Martín WAH-SUÁREZ, Nancy CONTRERAS-GARZA, Dionicio GALARZA-DELGADO   +4 more
doaj  

Clinical use of sodium bicarbonate in small animals: indications, electrolyte changes and survival outcome

Journal of Small Animal Practice, EarlyView.
Objectives The objective of the study was to describe the use of sodium bicarbonate in dogs and cats. Materials and Methods Retrospective descriptive study of animals administered sodium bicarbonate from 2019 to 2023 in a university teaching hospital.
L. Hoover, M. A. Oyama, E. L. Reineke
wiley   +1 more source