Results 121 to 130 of about 12,005 (312)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Variation and contact time of protective surface coating on fluoride release and recharge from glass ionomer restoration

Dental Journal
Background: Glass ionomer cement (GIC) is an effective restorative material known for its ability to release and recharge fluoride over an extended period.
Aya Thanoon AL-Dabbagh, Raya Jasim AL-Naimi   +1 more
doaj   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Surface micromorphological changes of glass ionomer following application of 1.23% acidulated phosphate fluoride: A scanning electron microscope study

Indian Journal of Dental Research, 2014
Objectives: The purpose of this study was to evaluate the surface micromorphological changes of conventional glass ionomer cement (GIC) (Fuji II, GC Corporation, Tokyo, Japan) and high strength, high viscosity GIC (Fuji IX GP, GC Corporation) subjected ...
Ektah Khosla, Sobha Kuriakose, Chintu Suderasen   +2 more
doaj   +1 more source

Prevention of Erosion and Abrasion by a High Fluoride Concentration Gel Applied at High Frequencies [PDF]

, 2010
Ziel dieser Studie war es, den maximal erreichbaren Schutz des Zahnschmelzes nach Erosion und Erosion in Verbindung mit Abrasion durch hochkonzentriertes Fluoridgel mit zusätzlichem Fluorid aus Zahnpasta zu ...
Kohnke, Sabrina
core  

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Effectiveness of Professionally Applied Fluoride Gels in Dental Caries Experience among Children and Adolescents: A Systematic Review and Meta-analysis

Journal of Indian Association of Public Health Dentistry
Objective: This systematic review and meta-analysis aimed to assess the effectiveness of professionally applied fluoride gel in dental caries experience among children and adolescents.
Neha Chauhan, Mahesh R Khairnar, Sarah Paul, Sachin Kumar Jadhav   +3 more
doaj   +1 more source

Evaluation of bond strength of orthodontic brackets without enamel etching [PDF]

, 2015
Background: to compare the shear bond strength of brackets with and without enamel etching. Material and Methods: In this study, 60 sound premolars were randomly divided into four different groups: 1- TXE group: Enamel etching + Transbond XT adhesive ...
Boruziniat, Alireza, Khazaei, Yegane, Moghaddas, Mohmmadjavad, Motaghi, Shiva   +3 more
core   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Effect of fluoride on friction between bracket and wire

Dental Research Journal, 2011
Background: Friction is usually encountered during sliding technique for orthodontic space closure. This study aims to investigate the effect of fluoride on frictional resistance between stainless steel orthodontic brackets and steel and NiTi arch wires.
Shiva Alavi, Ali Farahi
doaj   +1 more source