Results 221 to 230 of about 203,061 (356)

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

open access: yesArchiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová   +9 more
wiley   +1 more source

Addressing the Silent Pandemic: The Role of Italian Primary Care Paediatrics in Combating Antimicrobial Resistance

open access: yes
Acta Paediatrica, Volume 115, Issue 2, Page 285-289, February 2026.
Giovanni Cerimoniale   +11 more
wiley   +1 more source

Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 1, Page 235-244, January 2026.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu   +3 more
wiley   +1 more source

Potential of Eugenia brejoensis (Mazine) Essential Oil in Combating Multidrug‐Resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The genus Eugenia has a long history of use in traditional medicine for treating various conditions, including infectious diseases, gastrointestinal disorders, and skin problems. Essential oils derived from Eugenia species are known for their medicinal properties and have been studied for their antimicrobial and bioactive potential. This study
Jonathan Mandú de Araújo   +10 more
wiley   +1 more source

Chemical Constituents and Biological Activities of Oxandra (Annonaceae): A Review

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Oxandra (Annonaceae) comprises 29 species distributed across South and Central America. Despite this diversity, the genus remains under‐investigated. This study presents the first comprehensive review of the chemical composition and biological activities of Oxandra species, utilizing databases such as SciFinder, ScienceDirect, PubMed, and ...
Rayssa Cota Lopes   +4 more
wiley   +1 more source

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