Results 61 to 70 of about 1,873,639 (338)

Pediatric ACL injuries: evaluation and management [PDF]

Current Reviews in Musculoskeletal Medicine, 2013
The anterior cruciate ligament (ACL) is a stabilizing structure to both anterior translation of the tibia with respect to the femur as well as rotation of the knee joint. Children and adolescents are susceptible to these injuries, and there are some who believe the incidence of ACL injuries in this population is increasing due to year round single ...
Nathan A. Mall, George A. Paletta
openaire   +3 more sources

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration

Advanced Science, EarlyView.
Centimeter‐scale tendon organoids are engineered by mimicking the extracellular matrix and optimizing chemical cues to guide tendon stem/progenitor cells. These large, self‐assembling constructs overcome conventional size limitations and exhibit enhanced tenogenic differentiation, extracellular matrix production, and mechanical resilience. Their tissue‐
Tianshun Fang, Hong Zhang, Yuanhao Xie, Xiongfeng Li, Xi Liu, Zichen Wang, Yiwen Xue, Xiaohui Xia, Zetao Wang, Tingyun Lei, Ruifu Lin, Weiliang Shen, Bingbing Wu, Yishan Chen, Yanan Du, Xiao Chen, Zi Yin   +16 more
wiley   +1 more source

Increased knee torsional misalignment associated with femoral torsion is related to non-contact anterior cruciate ligament injury: a case–control study

Journal of Orthopaedic Surgery and Research
Background Altered axial biomechanics of the knee are recognized as a risk factor for non-contact anterior cruciate ligament (ACL) injury. However, the relationship of knee and segmental torsion to non-contact ACL and combined anterolateral ligament (ALL)
Dehua Wang, Hengkai Fan, Linlin Hu, Xi Liang, Wei Huang, Ke Li   +5 more
doaj   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

Advanced Science, EarlyView.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna, Jinshan He, Jiaxing Miao, Nargis Shaheen, Boyu Xia, Cankun Wang, Qin Ma, Matthew C Bernier, Bryan A Whitson, Nuo Sun, Jing Zhao, Yutong Zhao   +11 more
wiley   +1 more source

Cognitive Control After ACL Reconstruction: A Cross-Sectional Study on Impaired Proactive Inhibition Compared to Healthy Controls

Brain Sciences
Background/Objectives: Anterior cruciate ligament (ACL) injury is common in interaction sports and has severe physical and psychological consequences.
Jesús Jiménez-Martínez, Alejandro Gutiérrez-Capote, Iker Madinabeitia, David Cárdenas, Francisco Alarcón   +4 more
doaj   +1 more source

Anterior cruciate ligament (ACL) injury: correlation with MRI morphometry

The Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background This study aims to investigate the association between bony morphological features and ACL injury and to identify potential risk factors for the identification and prevention of ACL injuries.
Sagar Ganeshprasad Maheshwari, Rajesh Kuber, Purnachandra Lamghare, Joel Thomas, Rahul Arkar, Madhuri Avhad, T. Tharmalingam, D. S. Bhamare, Sanjana Katuri, Harish Nagraj, Shridhar Redla, M. Elsayad, Sofia Vrizidou   +12 more
doaj   +1 more source

ACL INJURY AND RETURN TO SPORT

European Journal of Health & Science in Sports, 2021
We followed 110 patients who had sustained an acute traumatic Haemarthrosis for a mean of 60 months. The arthrometer measurements within 90 days of injury revealed the injured knee was stable in 35 patients and unstable in 75. Thirty-five unstable patients had an ACL reconstruction within 90 days of injury.
Dorian Meta, Ilia Mazniku
openaire   +2 more sources

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source

Smoking and secondary ACL rupture are detrimental to knee health post ACL injury—a Bayesian analysis

Journal of Experimental Orthopaedics, 2023
Purpose To identify potential prognostic factors for patient‐reported outcomes in an Icelandic cohort of ACL injured subjects. Methods All knee MRI reports written in Iceland between the years 2001 to 2011 were read to identify individuals with a ...
Micah Nicholls, Thorvaldur Ingvarsson, Stephanie Filbay, Stefan Lohmander, Kristin Briem   +4 more
doaj   +1 more source