Results 121 to 130 of about 25,234 (218)

Association between glycemic variability and all-cause mortality in patients with sepsis-associated acute respiratory distress syndrome: a retrospective study based on the MIMIC database. [PDF]

J Thorac Dis
Ma Q, Guo J, Yang Y, Feng Y.
europepmc   +1 more source

Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology

The Journal of Physiology, EarlyView.
Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov, Katharina Ritzenhoff, Marie Gaulrapp, Lea Becker, Aiste Liutkute, Fitzwilliam Seibertz, Funsho E. Fakuade, Fleur E. Mason, Niels Voigt   +8 more
wiley   +1 more source

Atrial Cardiomyopathy and Atrial Fibrillation in Different Heart Failure Substrates. [PDF]

Arrhythm Electrophysiol Rev
Kantharia BK, Wu L, Hulsurkar MM, Karimzad K, Shah AN, Narasimhan B, Wehrens XH, Linz D, Heijman J.   +8 more
europepmc   +1 more source

The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis

The Journal of Physiology, EarlyView.
Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier, Anna S. Savchenko, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

Clinical outcomes of conduction system pacing versus right ventricular pacing in patients with atrioventricular block: a systematic review and meta-analysis of randomised controlled trials. [PDF]

Open Heart
Mojica JC, Interior J, Virata MC, Kasimieh O, Guingon A, Faizan MA, Rehman T, Fernandez FC.   +7 more
europepmc   +1 more source

Transformer‐Based Contextual Modeling for Predicting Calories From Recipes

Applied AI Letters, Volume 7, Issue 3, October 2026.
A transformer‐based regression model with token‐level attention pooling is proposed for predicting calorie content directly from unstructured recipe text. By fine‐tuning RoBERTa in an end‐to‐end manner, attention is learned to be focused on calorie‐relevant tokens such as ingredients, fats, and cooking methods.
Md. Siam Ansary, Amina Brinto
wiley   +1 more source

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model. [PDF]

Front Immunol
Hutschalik T, Dasí A, Riebel LL, Wiendels M, Bakker F, Beckers LJAM, Kriege KC, Valster SM, Vulders RCM, Özgül O, Peyronnet R, Rodriguez B, Argenziano M, Schotten U, Matsa E.   +14 more
europepmc   +1 more source

Genomic Contributors to Congenital Diaphragmatic Hernia: Results of Exome Sequencing in 560 Probands and Cross Reference of Findings in an Independent Cohort

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1821-1831, August 2026.
ABSTRACT There is a strong genetic contribution to the etiology of congenital diaphragmatic hernia (CDH). This study evaluated genetic testing results and diagnostic yield for fetuses and children with CDH. This was a retrospective cohort study of exome sequencing (ES) performed at GeneDx for fetuses and children ≤ 18 years of age with CDH compared ...
Justin Blair, Kevin Carratu, Natalie E. Rintoul, Holly L. Hedrick, William H. Peranteau, Catherine M. Avitabile, Kirsty McWalter, Paul Kruszka, Ian D. Krantz, K. Taylor Wild   +9 more
wiley   +1 more source

Dual CD73/A_2AR blockade modulates the neurotoxic astrocyte phenotype without disrupting core inflammatory signaling. [PDF]

Front Pharmacol
Mihajlovic K, Dragic M, Adzic Bukvic M, Martic T, Stevanovic I, Vinit S, Bleuzé M, Mansart A, Adam L, Nedeljkovic N.   +9 more
europepmc   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1807-1813, August 2026.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg, Savannah Coppersmith, Owen Merritt, Amer Heider, Adam Helms, Thomas Michniacki, Jack Luxford, Sarah Josephi‐Taylor, Philip Roberts, Joshua Meisner   +9 more
wiley   +1 more source