Results 141 to 150 of about 22,918 (266)

A novel two-component signal transduction system in propionibacterium acnes and its association with a putative extracellular signalling peptide [PDF]

open access: yes, 2011
Propionibacterium acnes, a resident micro-organism of human skin, is thought to be involved in the development of inflammatory acne, which is an exclusive human disease affecting more than 80% of the whole population. Quorum sensing is the regulation of
Guan, Shuang
core  

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Serum Testosterone Level in Female Patients with Adult Acne and Its Correlation with Acne Severity

open access: yesNepal Journal of Dermatology, Venereology & Leprology
Introduction: Acne is one of the common problems in the adult female population. Androgen excess, indicated by high serum testosterone levels, has been implicated as a cause for adult-onset acne, though studies correlating testosterone levels with acne ...
Punam Mishra   +2 more
doaj   +1 more source

Overview of Biology, Pathophysiology and Treatment of Acne Vulgaris

open access: yes, 2018
Acne vulgaris is a chronic multifactorial inflammatory disease of sebaceous gland mainly in adolescents.Pathogenesis of acne involves four main factors; excess sebum production, abnormal keratinization within the follicle, colonization of P.
Takeda, Ayano
core  

Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults

open access: yes, 2012
Background: Genetic and environmental components may contribute to acne causation. Objective: We sought to assess the impact of family history, personal habits, dietary factors, and menstrual history on a new diagnosis of moderate to severe acne. Methods:
ATZORI, LAURA   +32 more
core   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

open access: yesAndrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben   +3 more
wiley   +1 more source

Impact of Gentamicin‐Impregnated Collagen Sponge on the Incidence of Access Related Infections After Full‐Support Microaxial Flow Pump Therapy

open access: yesArtificial Organs, EarlyView.
Local application of gentamicin for wound closure after full‐support microaxial flow pump therapy. ABSTRACT Background Surgically implanted microaxial flow pumps (mAFP) are increasingly used for cardiogenic shock treatment. Standard mAFP explantation is performed bedside with a shortening of the vascular prosthesis, which may represent a potential ...
Gaik Nersesian   +11 more
wiley   +1 more source

Infectious bacterial keratitis management in a Swedish region: Risk factors, treatment and time‐to‐resolution

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth   +5 more
wiley   +1 more source

Fillers for the improvement in acne scars

open access: yes, 2015
Uwe Wollina,1 Alberto Goldman2 1Department of Dermatology and Allergology, Academic Teaching Hospital, Dresden-Friedrichstadt, Dresden, Germany; 2Clinica Goldman, Porto Alegre, Rio Grande do Sul, Brazil Abstract: Acne is a common inflammatory disease ...
Wollina U, Goldman A
core  

One‐Year Effectiveness of Upadacitinib in Perianal Crohn's Disease: A Real‐World GETAID Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a real‐world cohort of patients with highly refractory perianal Crohn's disease, upadacitinib induced clinical remission at 12 months in 26% of patients with fistulizing disease and 25% of those with isolated anal ulcerations. ABSTRACT Introduction Upadacitinib (UPA) is effective for treating luminal Crohn's disease (CD), but data on perianal CD ...
Nicolas Richard   +13 more
wiley   +1 more source

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