Results 241 to 250 of about 135,067 (309)

Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro

JOR SPINE, Volume 9, Issue 2, June 2026.
Integrated secretome and phosphoprotein profiling of human nucleus pulposus cells revealed that IL‐1β and TLR2/6 activation induce a shared degenerative program, defined by consistent upregulation of IL‐6, IL‐8, GRO‐α, ICAM‐1, and MMP‐7 and convergence on NF‐κB/AP‐1 signaling.
Exarchos Kanelis, Andrea Nüesch, Joseph Snuggs, Christine Lyn Le Maitre, Leonidas G. Alexopoulos   +4 more
wiley   +1 more source

Comparison of Substances in Combined Oral Contraceptives Used in Acne Vulgaris, Hirsutism, Migraine, and Dysmenorrhea. [PDF]

Med Sci Monit
Wójcikiewicz P, Durlej G, Satora M, Tarkowski R, Kułak K.   +4 more
europepmc   +1 more source

Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age‐, Sex‐, and BMI‐Matched Pilot Study

JOR SPINE, Volume 9, Issue 2, June 2026.
Chronic low back pain in patients without advanced disc degeneration is associated with gut microbiome dysbiosis, marked by reduced microbial diversity and altered bacterial composition. These findings support a gut–disk axis in which impaired gut barrier integrity and systemic inflammation may contribute to disc inflammation, nociceptive fiber ...
Stone Sima, Thomas Jeffries, Alisha Sial, Suhani Sharma, Neha Chopra, Fan Zhang, Georgina Hold, Wentian Li, Ji Tu, Victor Chen, Ashish Diwan   +10 more
wiley   +1 more source

Keratinocyte-Associated Biomarkers Reveal Pathogenic Mechanisms in Acne. [PDF]

FASEB Bioadv
Cai S, Lin Y, Xie H, Ao X, Liu Q, Huang L.   +5 more
europepmc   +1 more source

Intradiscal Cutibacterium acnes Sustains Modic Type 1‐Like Lesions Over Time in a Rat Lumbar Endplate Injury Model

JOR SPINE, Volume 9, Issue 2, June 2026.
Intradiscal C. acnes injection sustained MC1‐like lesions with persistent neutrophil sustenance in an etiology‐specific lumbar MC rat model. This suggests that patients with bacterial MC etiology may persist in painful MC1, highlighting C. acnes and neutrophils as potential targets to promote MC1‐to‐MC2 conversion and improve pain and disability ...
Irina Heggli, Alon Lai, Denise Iliff, Marco D. Burkhard, Niklas Koehne, Harsev Singh, Jonathan J. Huang, Alan C. Seifert, Damien Laudier, Noah Bonnheim, Levon Rodriguez, Timothy D. Jacobsen, James C. Iatridis   +12 more
wiley   +1 more source

Long-term impact of antibiotic exposure duration on recurrence and microbial resistance in moderate-to-severe acne: a real-world retrospective analysis. [PDF]

Front Med (Lausanne)
Wang L, Wang H, Zhou J, Chen L, Xu M, Zhang J.   +5 more
europepmc   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Multidisciplinary Approach to Complex Lower Extremity Limb Salvage in Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome: A Case Report. [PDF]

Microsurgery
Talanker MM, Basta AV, Do T, Tung R, Allen A, Martin M, Ruygrok BL, Kellam PJ, Trost JG, Bhadkamkar MA.   +9 more
europepmc   +1 more source

Safety and Preliminary Clinical Effects of a Herbal Balance Solution in Mild-To-Moderate Acne Vulgaris: An Open-Label, Single-Arm Pilot Study. [PDF]

J Cosmet Dermatol
Teng X, Shu X, Huo W, Li Z, Zou L, Li L, Wang X.   +6 more
europepmc   +1 more source

Dermocosmetics in Acne Vulgaris: South African Consensus Recommendations With a Focus on Skin of Color. [PDF]

J Cosmet Dermatol
Visser WI, Kannenberg SM, Prevost A, Khoza N, Pillay L, Wiid KJ, Heydenrych IR.   +6 more
europepmc   +1 more source