The exposomal imprint on rosacea: More than skin deep
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki +3 more
wiley +1 more source
DNA Methylation at cg18095732 Modulates ZDHHC20 Expression and Decreases Acne Vulgaris Risk. [PDF]
Gong K, Ji X, Wu S, Zhao DD, Zhu M.
europepmc +1 more source
Forty‐three HS specialists from 22 European countries reported adherence to HS guidelines and use of antibiotics before biologics despite limited efficacy and rapid relapse (49% within 1–3 months). Seventy‐nine per cent supported short‐term biologics for severe Hurley I disease.
Georgios Nikolakis +41 more
wiley +1 more source
RETRACTED: Kola-Mustapha et al. Network Pharmacology and Molecular Modeling to Elucidate the Potential Mechanism of Neem Oil against <i>Acne vulgaris</i>. <i>Molecules</i> 2023, <i>28</i>, 2849. [PDF]
Kola-Mustapha AT +3 more
europepmc +1 more source
Hair follicle stem cell fate supports distinct clinical endotypes in hidradenitis suppurativa
Hair follicles (HFs) were extracted from skin biopsies. From these, original sequencing data were obtained and integrated with two independent studies to build a HF single‐cell transcriptomic atlas. It enabled delineating the fate of HF stem cells.
Audrey Onfroy +17 more
wiley +1 more source
An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer. [PDF]
Balado-Simó P +6 more
europepmc +1 more source
Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami +6 more
wiley +1 more source
Association Between Altered Gut Microbiota and Acne Vulgaris: A Comparative Study of Trimethylamine N-Oxide Levels in Patients and Healthy Controls. [PDF]
Bal Bayazıtlı EC +6 more
europepmc +1 more source

