Results 31 to 40 of about 71,028 (246)

Efficacy and tolerability of fenfluramine with concomitant potassium bromide in patients with Dravet syndrome

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To assess the efficacy and tolerability of fenfluramine (FFA) with concomitant potassium bromide (BR) in patients with Dravet syndrome (DS). Methods This multicenter retrospective study, conducted within the German compassionate use program, analyzed BR doses and serum levels before and after FFA initiation, adverse events (AEs ...
Milka Pringsheim   +13 more
wiley   +1 more source

Autophagy‐Targeting Nanomedicine: Strike at the Heart of the Cancer via Precise Modulation of Autophagy

open access: yesExploration, EarlyView.
This review emphasizes the critical role of autophagy in cancer treatment, highlighting the development of autophagy‐targeting nanomedicines and their applications in combination therapies. It explores how nanoplatforms can effectively regulate autophagy, underscoring the potential of integrating autophagy modulation with other treatment strategies to ...
Zhouyi Sun   +10 more
wiley   +1 more source

Impact of Endocrine‐Disrupting Chemicals (EDCs) Used in the Food Industry on Endocrine Abnormalities

open access: yesFood Safety and Health, EarlyView.
This review was conducted to examine the relationship between hormone disruption and other endocrine abnormalities in the context of the constant consumption of genetically modified foods and overexposure to chemicals used directly and indirectly in the agrifood industry.
Perla D. Serrano‐López   +3 more
wiley   +1 more source

The microbiome in cancer

open access: yesiMeta, EarlyView.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin   +50 more
wiley   +1 more source

Emotion and peer problems in autistic adolescents: The role of puberty, school adjustment and bullying

open access: yesJCPP Advances, EarlyView.
Abstract Background Emotion and peer problems tend to increase in autistic young people during adolescence. However, the extent to which endogenous (e.g., pubertal maturation) and exogenous (e.g., school adjustment, bullying) factors contribute to trajectories of emotion and peer problems in autistic young people is unclear. Methods Using data from the
Erin O. Dawe‐Lane   +3 more
wiley   +1 more source

Laser Disinfection Acts as Biofilm‐Disrupter in Periprosthetic Joint Infection (PJI)

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Infections after joint arthroplasties represent a devastating and progressively escalating complication with increased morbidity and mortality. The eradication of biofilms from infected implants is still an unsolved challenge. The erbium‐doped yttrium aluminum garnet (Er:YAG) laser, which delivers high‐energy light for rapid tissue ablation ...
Lukas K. Kriechbaumer   +11 more
wiley   +1 more source

Machine learning‐assisted prediction of clinical responses to periodontal treatment

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis is among the most prevalent chronic inflammatory conditions globally, and is associated with bone resorption, tooth loss, and systemic complications. While its treatment is largely standardized, individual outcomes vary, with some patients experiencing further disease progression despite adherence. Methods We developed
Balazs Feher   +5 more
wiley   +1 more source

Management of paediatric ulcerative colitis, part 1: Ambulatory care—An updated evidence‐based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine   +24 more
wiley   +1 more source

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