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Ultrasound contrast agents: acoustic characterization and diagnostic imaging
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Acoustic Signatures of Submicron Contrast Agents
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2004Previous studies have revealed that hard-shelled submicron contrast agents exhibit large relative expansions and strong acoustical echoes that can be observed experimentally, and predicted by theoretical simulations. In this paper, we study harmonic imaging and pulse-pair imaging techniques designed to assist in the differentiation of these contrast ...
Divia N, Patel +3 more
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Acoustic Sizing of an Ultrasound Contrast Agent
Ultrasound in Medicine & Biology, 2010Because the properties of ultrasound contrast agent populations after administration to patients are largely unknown, methods able to study them noninvasively are required. In this study, we acoustically performed a size distribution measurement of the ultrasound contrast agent Definity(®).
Maresca, David +7 more
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Acoustic behaviour of current ultrasound contrast agents
Ultrasonics, 2000A general law gives the approximate change in signal level obtained in a particular imaging mode when a suitable contrast agent is added. It also shows that reduction of background signals is essential to overcome limitations found mainly in conventional (linear) ultrasound contrast imaging.
V, Uhlendorf, F D, Scholle, M, Reinhardt
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Acoustic characterisation of Nycomed's NC100100 contrast agent
1998 IEEE Ultrasonics Symposium. Proceedings (Cat. No. 98CH36102), 2002The authors have developed in vitro methods to characterise ultrasound contrast agents, based on correlating acoustic attenuation spectra with particle size measurements. The methods have been used to characterise Nycomed's NC100100, and to compare this with Infoson and with an experimental polymer-encapsulated contrast agent.
L. Hoff, P.C. Sontum
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Optical and acoustical interrogation of submicron contrast agents
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2002Unlike conventional ultrasound contrast agents with a diameter of several microns, in this paper we explore the use of submicron contrast agents for the detection and localization of lymph nodes. The submicron agents are gas-filled, double-walled microspheres that rupture when exposed to ultrasound energy at megahertz frequencies.
Divia, Patel +4 more
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Acoustic bubble sorting for ultrasound contrast agent enrichment
Lab Chip, 2014Resonant microbubbles are sorted from a polydisperse ultrasound contrast agent suspension in an acoustic bubble sorting chip.
Segers, T.J., Versluis, Michel
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Acoustic characterization of single ultrasound contrast agent microbubbles
The Journal of the Acoustical Society of America, 2008Individual ultrasound contrast agent microbubbles (BR14) were characterized acoustically. The bubbles were excited at a frequency of 2MHz and at peak-negative pressure amplitudes of 60 and 100kPa. By measuring the transmit and receive transfer functions of both the transmit and receive transducers, echoes of individual bubbles were recorded ...
Sijl, J. +6 more
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