Results 171 to 180 of about 119,470 (290)

Observations of marine animal interactions with a small tidal turbine. [PDF]

open access: yesPLoS One
Cotter E   +8 more
europepmc   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee   +9 more
wiley   +1 more source

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

open access: yesAdvanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre   +12 more
wiley   +1 more source

Temporal Attentive Pooling for Acoustic Event Detection.

open access: yesTemporal Attentive Pooling for Acoustic Event Detection.
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

open access: yesAdvanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi   +13 more
wiley   +1 more source

Single‐Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label‐Free Metabolic Microscopy

open access: yesAdvanced Science, EarlyView.
Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim   +7 more
wiley   +1 more source

In Situ Characterisation of Hydrogels via Dynamic Interface Printing

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels have become pivotal materials for tissue engineering, robotics, biomedical devices, and sensing applications due to their diverse material compositions and tunable mechanical properties. While significant effort has focused on developing novel manufacturing approaches such as extrusion bioprinting and light‐based fabrication methods,
Callum Vidler   +2 more
wiley   +1 more source

Environmental Noise Dataset for Sound Event Classification and Detection. [PDF]

open access: yesSci Data
Fredianelli L   +5 more
europepmc   +1 more source

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