Results 71 to 80 of about 1,935 (199)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A Simple Pump-Free Approach to Generating High-Throughput Microdroplets Using Oscillating Microcone Arrays

Micromachines
Droplet generation is crucial in various scientific and industrial fields, such as drug delivery, diagnostics, and inkjet printing. While microfluidic platforms enable precise droplet formation, traditional methods often require costly and complex setups,
Erturan Yetiskin, Ilayda Erdem, Sinan Gucluer, Adem Ozcelik   +3 more
doaj   +1 more source

Continuous Particle Aggregation and Separation in Acoustofluidic Microchannels Driven by Standing Lamb Waves

Micromachines, 2022
In this study, we realize acoustic aggregation and separation of microparticles in fluid channels driven by standing Lamb waves of a 300-μm-thick double-side polished lithium-niobate (LiNbO3) plate.
Jin-Chen Hsu, Chih-Yu Chang
doaj   +1 more source

Imaging Local Acoustic Pressure in Microchannels [PDF]

, 2015
A method for determining the spatially resolved acoustic field inside a water-filled microchannel is presented. The acoustic field, both amplitude and phase, is determined by measuring the change of the index of refraction of the water due to local ...
Ende, D. van den, Frentrop, R.N., Herek, J.L., Mugele, F., Oever, J.J.F. van 't, Offerhaus, H.L., Wijnperlé, D.   +6 more
core   +1 more source

Capture, Confine, Characterize: High‐Throughput Dielectrophoresis‐Based Single‐Cell Microfluidics Platform to Analyze Mammalian and Yeast Cells Using Raman Spectroscopy

Small, EarlyView.
Traditional single‐cell analysis lacks the capacity for real‐time monitoring. This study presents Microfluidic dielectrophoretic Arresting System (MiDAS), a microelectrofluidic platform using dielectrophoresis for single‐cell and droplet trapping. MiDAS immobilizes diverse samples (cells, beads, droplets) for optical imaging and Raman spectroscopy. Its
Bum‐Joon Jung, Allison Hohreiter, Runjie Chen, Dylan Cook, Linus Hansen, Sunny Taylor, Koseki J. Kobayashi‐Kirschvink, Joseph Chaiken, Supratik Guha, Anindita Basu   +9 more
wiley   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

Small, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi, Tijana Maric, Isidro Badillo‐Ramírez, Juliane Fjelrad Christfort, Matteo Tollemeto, Carmen Milan Guimera, Casper Nisula, Giulia Zappalá, Laura De Vittorio, Marta Rubio‐Huertas, Sungyeong Kim, Ziqiao Li, Morten Bo Søndergaard Svendsen, Zhongyang Zhang, Anja Boisen   +14 more
wiley   +1 more source

Acoustofluidic methods in cell analysis

TrAC Trends in Analytical Chemistry, 2019
Cellular analysis is a central concept for both biology and medicine. Over the past two decades, acoustofluidic technologies, which marry acoustic waves with microfluidics, have significantly contributed to the development of innovative approaches for cellular analysis.
Yuliang, Xie, Hunter, Bachman, Tony Jun, Huang   +2 more
openaire   +3 more sources

Ultrasound-Induced Cell–Cell Interaction Studies in a Multi-Well Microplate

Micromachines, 2014
This review describes the use of ultrasound for inducing and retaining cell-cell contact in multi-well microplates combined with live-cell fluorescence microscopy. This platform has been used for studying the interaction between natural killer (NK) cells
Martin Wiklund, Athanasia E. Christakou, Mathias Ohlin, Ida Iranmanesh, Thomas Frisk, Bruno Vanherberghen, Björn Önfelt   +6 more
doaj   +1 more source

Comparison of Acoustic Streaming Flow Patterns Induced by Solid, Liquid and Gas Obstructions

Micromachines, 2020
In this study, acoustic streaming flows inside micro-channels induced by three different types of obstruction—gaseous bubble, liquid droplet and solid bulge—are compared and investigated experimentally by particle tracking velocimetry (PTV) and ...
Hsin-Fu Lu, Wei-Hsin Tien
doaj   +1 more source

Microscale Concert Hall Acoustics to Produce Uniform Ultrasound Stimulation for Targeted Sonogenetics in hsTRPA1‐Transfected Cells

Advanced NanoBiomed Research, 2022
Ultrasound neuromodulation has rapidly developed over the past decade, a consequence of the discovery of strain‐sensitive structures in the membrane and organelles of cells extending into the brain, heart, and other organs. A key limitation to its use in
Aditya Vasan, Florian Allein, Marc Duque, Uri Magaram, Nicholas Boechler, Sreekanth H. Chalasani, James Friend   +6 more
doaj   +1 more source